中国实用神经疾病杂志Issue(12):26-28,3.
血浆辅助治疗对颅脑损伤合并凝血功能障碍患者预后的影响
Study on the effect of plasma adjuvant therapy on the prognosis of patients with traumatic brain injury compli-cated with coagulation disorders
肖华1
作者信息
- 1. 重庆市荣昌县人民医院神经外科 重庆 402460
- 折叠
摘要
Abstract
Objective To Study the effect of plasma adjuvant therapy on the prognosis of patients with traumatic brain in-jury complicated with coagulation disorders.Methods 60 patients with craniocerebral injury complicated with coagulation dys-function were included and divided into observation group and control group. Patients in observation group were given the plas-ma auxiliary treatment. Patients in control group were given routine treatment. The serum level of blood coagulation function and related biochemical indicators were detected after treatment for 3 d ,7 d and 14 d.Results The differences of levels of MBP ,NSE before treatment between two group were not significant (P>0.05).The level of NSE after treatment was lower than that before treatment. The difference was statistical significanct (P<0.05).The levels of MBP after treatment for 3 d were higher than that before treatment.The difference was statistical significance (P< 0.05).The levels of MBP after treat-ment for 7 d began to decline.The levels of MBP after treatment for 7 d ,14 d in observation group were lower than those in con-trol group.The difference was statistical significance (P<0.05).The differences of levels of blood coagulation before treatment between two group were not significant (P>0.05).The levels of blood coagulation after treatment were lower than those be-fore treatment(P<0.05).The levels of PT 、APTT、TT、FIB after treatment in observation group were lower than those of the control group.The difference was statistical significance (P< 0.05).The difference of levels of GCS score before and after treatment was not significant (P> 0.05).Conclusion Plasma adjuvant therapy effectively improves coagulation function ,re-duces the incidence of inflammatory reaction ,but Can not obviously improve the prognosis of patients with traumatic brain inju-ry.关键词
血浆辅助/颅脑损伤/凝血功能障碍Key words
Plasma assisted/Craniocerebral injury/Blood coagulation dysfunction分类
医药卫生引用本文复制引用
肖华..血浆辅助治疗对颅脑损伤合并凝血功能障碍患者预后的影响[J].中国实用神经疾病杂志,2014,(12):26-28,3.