摘要
Abstract
Objective To study and analyze the effectiveness and safety of acyclovir in the treatment of children with viral meningitis .Methods 76 children with viral meningitis in our hospital from August 2010 to June 2013 were selected as research objects ,and were randomly divided into control group(ribavirin group)38 cases and observation group(acyclovir group)38 ca-ses ,then the total effective rates of mild and severe viral meningitis ,incidence of adverse reaction and NSE ,PCT ,IL-6 levels in serum ,cerebrospinal fluid before and after the treatment of two groups were compared .Results The total effective rates of mild and severe viral meningitis in observation group were respectively higher than those of control group ,incidence of adverse reaction was lower than that of control group ,serum and cerebrospinal fluid NSE ,PCT and IL-6 levels after the treatment were all lower than those of observation group before treatment and those of control group after the treatment ,all(P<0 .05) ,there were all significant differences .Conclusion The effect and safety of acyclovir in the treatment of children with viral meningitis is relatively better ,and it plays an active role in improving the nerve function and controlling the inflammation .关键词
阿昔洛韦/小儿病毒性脑膜炎/安全性Key words
acyclovir/children with viral meningitis/effect/safety分类
医药卫生