中国实用神经疾病杂志Issue(13)：15-17,3.
强化降脂对缺血性脑卒中患者血脂及颈动脉粥样硬化的影响
Clinical study on the effect of intensive lipid lowering on blood lipids and carotid atherosclerosis in patients with ischemic stroke
摘要
Abstract
Objective To investigate the effect of Intensive lipid lowering on blood lipids and carotid atherosclerosis in pa-tients with ischemic stroke .Methods Cholesterol ,carotid artery plaque of two groups were monitored ,during the follow-up , the incidence of cerebrovascular adverse events and adverse reactions of the two groups were recorded .Results After treat-ment ,TC ,TG ,LDL-C and apoB levels and CIM T and plaque area of the two groups were significantly lower than those before treatment ;HDL-C ,apoA and LpA levels were significantly increased ,and the changes of observation group were more obvi-ous ;During the follow up for 6 months ,the TIA ,cerebral infarction ,and recurrence rate of observation group were signifi-cantly lower than those of the control group .The difference was statistically significant (P<0.05) .The difference of inci-dence of adverse reactions of the two groups was not statistically significant (P>0.05) .Conclusion Intensive lipid-lowering for patients with ischemic stroke can effectively improve blood lipid levels ,reduce the degree of carotid atherosclerosis ,improve the therapeutic effectiveness ,reduce the incidence of cerebrovascular adverse events ,and does not increase the incidence of ad-verse reactions ,It is a safe and effective method of treatment .关键词
强化降脂/缺血性脑卒中/血脂/颈动脉粥样硬化/阿托伐他汀Key words
Intensive lipid-lowering/Ischemic stroke/Lipids/Carotid atherosclerosis/Atorvastatin分类
医药卫生引用本文复制引用
张俊湖,褚旭,彭友敬,冯勋刚,丁国娟..强化降脂对缺血性脑卒中患者血脂及颈动脉粥样硬化的影响[J].中国实用神经疾病杂志,2014,(13):15-17,3.基金项目
2010省卫生适宜技术成果转化计划 （）
