中国实用神经疾病杂志Issue(14):30-31,2.
新生儿缺氧缺血性脑病108例临床分析
Clinical analysis of 108 cases of newborn hypoxic-ischemic encephalopathy
吴铭辉 1史长松2
作者信息
- 1. 郑州大学第四附属医院儿科 郑州 450044
- 2. 郑州大学人民医院 河南省人民医院 郑州 450003
- 折叠
摘要
Abstract
Objective To explore the methods for diagnosis and treatment of newborn hypoxic ischemic encephalopathy (HIE).Methods The etiology ,pathogenesis ,clinical manifestations ,auxiliary examination ,the methods of treatment and therapeutic effect of 108 cases of HIE were retrospectively analyzed.108 cases of HIE were randomly divided into four groups , 27 cases in each group. On the basis of comprehensive treatment ,each group was treated with ganglioside (GM-1) or cytidine diphosphate choline or magnesium sulfate respectively.Results The diagnosis of HIE mainly depended on clinical manifesta-tions. It was helpful to the diagnosis of HIE to take the examination of B ultrasound ,CT and MRI. GM-1 or cytidine diphos-phate choline had significant effectiveness ,compared with the control group respectively. There was statistically significant difference (AP<0.01 BP<0.05).Magnesium sulfate had certain curative effect.Conclusion Examination of MRI helps deter-mine the severity and prognosis of HIE. There is a good effectiveness to use the GM-1 or cytidine diphosphate choline ,and It is worthy of clinical promotion.关键词
新生儿/缺氧缺血性脑病/临床分析Key words
Newborns/Hypoxic-ischemic encephalopathy/Clinical analysis分类
医药卫生引用本文复制引用
吴铭辉,史长松..新生儿缺氧缺血性脑病108例临床分析[J].中国实用神经疾病杂志,2014,(14):30-31,2.