中国实用神经疾病杂志Issue(15)：10-12,3.
丙泊酚在高血压脑出血手术患者中的应用观察
Observation of the effect of propofol on surgical patients with hypertensive intracerebral hemorrhage
陈友利 1郭瑞 1王立勋1
作者信息
- 1. 南方医科大学附属小榄医院麻醉科 中山 528415
- 折叠
摘要
Abstract
Objective To observe the clinical effect of propofol on surgical patients with hypertensive intracerebral hemor-rhage .Methods The clinical data of 90 cases with hypertensive cerebral hemorrhage in our hospital were taken for retrospec-tive analysis .According to different methods of anesthesia , they were divided into the propofol group and the midazolam group ,and 45 cases in each group .Propofol and midazolam were used for anesthesia respectively .The HR and MAP changes and oxygen uptake rate (CEO2 ) for the two groups before and after surgery were compared .Results After 30 min of surgery , HR and MAP in the two groups returned to normal ,and there was no significant difference ,P>0 .05 .Ten minutes intraopera-tive and postoperative ,propofol group HR and MAP changes were more obvious ,there was statistical significant difference ,P<0 .05 .The midazolam group was with less obvious changes in HR and MAP ,and there was not statistical significance ,P>0 .05 .Before surgery ,preoperative oxygen uptake rate of the two groups were without significant difference , P>0 .05 .Ten minutes for the propofol group ,the postoperative oxygen uptake was significantly higher than that of patients in the midazolam group ,P<0 .05 .Conclusion Propofol has the advantage of decreasing cerebral metabolic rate and peripheral vascular resist-ance .Its effect in the implementation of surgery and anesthesia for hypertensive cerebral hemorrhage is better than midazolam .关键词
丙泊酚/咪达唑仑/高血压脑出血Key words
Propofol/Midazolam/Hypertensive intracerebral hemorrhage分类
医药卫生引用本文复制引用
陈友利,郭瑞,王立勋..丙泊酚在高血压脑出血手术患者中的应用观察[J].中国实用神经疾病杂志,2014,(15):10-12,3.
