中国实用神经疾病杂志Issue(18)：27-28,2.
不同剂量 rt-PA 静脉溶栓治疗急性脑梗死的临床疗效
The curative effect of different doses of rt-PA intravenous thrombolysis treating patients with acute cerebral infarction
张国昌1
作者信息
- 1. 山东济宁市第一人民医院 济宁 272000
- 折叠
摘要
Abstract
Objective To investigate the the curative effect of different doses of rt-PA intravenous thrombolysis treating patients with acute cerebral infarction.Methods 82 patients with acute cerebral infarction in our hospital from February 2010 to November 2012 were randomly divided into the intravenous thrombolysis group A (n= 41 ,0 .6 mg/kg ) and the intravenous thrombolysis group B (n= 41 ,0 .9 mg/kg).The neural function defect score (NIHSS) and complications incidence of two groups were compared.Results The NIHSS of two groups after treatment were more than these before treatment ,but had no significant difference in different stages of the two groups after treatment. The incidence of adverse reactions in group B was higher than that in group A.Conclusion Rt-PA intravenous thrombolysis can significantly improve the prognosis of patients with acute cerebral infarction ,but no significant correlation between therapeutic effect and dose size.Large dose of rt-PA can increase the bleeding risk .关键词
rt-PA/静脉溶栓/急性脑梗死Key words
Rt-PA/Intravenous thrombolysis/Acute cerebral infarction分类
医药卫生引用本文复制引用
张国昌..不同剂量 rt-PA 静脉溶栓治疗急性脑梗死的临床疗效[J].中国实用神经疾病杂志,2014,(18):27-28,2.
