中国实用神经疾病杂志Issue(19)：27-29,3.
艾地苯醌治疗缺血性脑卒中后抑郁疗效观察
The curative efficacy of idebenone on ischemic post-stroke depression
摘要
Abstract
Objective To evaluate the clinical efficacy and safety of idebenone on ischemic post-stroke depression.Methods A total of 64 patients with ischemic post-stroke depression were randomly divided into idebenone group (n=32)and control group(n=32).Patients in idebenone group received conventional treatment ,psychotherapy and idebenone administration ,while patients in control group received conventional treatment and psychotherapy only.Patients were evaluated by the HAMD and SSS before treatment ,and 4 weeks after treatment.Results After treatment ,the HAMD score of idebenone group were signif-icantly lower than that of the control group(P<0.05) and SSS also decreased significantly(P<0.05).The curative efficacy on post-stroke depression and neurological function deficit in idebenone group were better than those of control group.Conclusion Idebenone can effectively treat post-stroke depression and ameliorate the neurological function without obvious side effect.关键词
艾地苯醌/脑卒中后抑郁/脑梗死Key words
Idebenone/Post-stroke depression/Cerebral infarction分类
医药卫生引用本文复制引用
张翼,陈继华,符鹏程..艾地苯醌治疗缺血性脑卒中后抑郁疗效观察[J].中国实用神经疾病杂志,2014,(19):27-29,3.基金项目
郴州市第一人民医院院级科研项目 （）
