中国实用神经疾病杂志Issue(20)：18-19,2.
吉非替尼对非小细胞肺癌脑转移的预后分析
Effects of gefitinib on the prognosis of patients with non-small cell lung cancer brain metastases
摘要
Abstract
Objective To investigate the effects of gefitinib on the prognosis of patients with non-small cell lung cancer brain metastases. Methods The clinical data of 70 patients with non-small cell lung cancer brain metastases in our hospital were retrospectively analyzed. Patients were divided into the treatment group (n=35 ,treated with whole brain radiotherapy ) and the control group (n=35 ,treated with whole brain radiotherapy combined with gefitinib ) according to the different treat-ment methods. The curative effects and adverse reactions were compared. Results The efficiency (48.57% ) ,disease control rate (77.14% ) and CR patients (17.14% ) of treatment group were higher than these of control group (34.28% ,60.00% and 8.57% ) ,respectively ;The PD rate (22.86% ) of treatment group was lower than that of control group ;The adverse reaction incidence between two groups had no significant difference. Conclusion Gefitinib combined with whole brain radiotherapy have less toxic side effects and better curative effect on patients with non-small cell lung cancer brain metastases.关键词
吉非替尼/非小细胞肺癌/脑转移/全脑放疗Key words
Gefitinib/Non-small cell lung cancer/Brain metastases/Whole brain radiotherapy分类
医药卫生引用本文复制引用
郑积华,周娟,谢波,徐志勇,英娟,林金容,张为民..吉非替尼对非小细胞肺癌脑转移的预后分析[J].中国实用神经疾病杂志,2014,(20):18-19,2.基金项目
广东省科技计划项目（No畅2012B031800181）广东省医学科研基金 （）
