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自体骨髓间充质干细胞移植辅助高压氧治疗高血压脑出血临床观察

张化明 杨冰

中国实用神经疾病杂志Issue(21):15-17,3.
中国实用神经疾病杂志Issue(21):15-17,3.

自体骨髓间充质干细胞移植辅助高压氧治疗高血压脑出血临床观察

Curative effect of autologous bone marrow mesenchymal stem cells transplantation combined with hyperbaric oxygen on treating patients with hypertensive cerebral hemorrhage

张化明 1杨冰2

作者信息

  • 1. 武汉市武钢总医院神经外科 武汉 430080
  • 2. 武汉市第八医院内一科 武汉 430014
  • 折叠

摘要

Abstract

Objective To investigate the curative effect of autologous bone marrow mesenchymal stem cells (BMSCs) transplantation combined with hyperbaric oxygen (HBO) on treating patients with hypertensive cerebral hemorrhage (HCH)· Methods 102 patients with HCH were randomly divided into control group (treated with HBO therapy) and treatment group (treated with BMSCs plus HBO therapy) .The neurological function impairment of two groups were compared by the National Institute of Health stroke scale(NIHSS) ,activities of daily living(Barthel index) ,Glasgow out-come scale(GOS) and Karnofsky performance scale(KPS) before and after 6 months treatment .Results Compared with control group ,there were lower NIHSS score and higher Barthel index in the treatment group and the GOS and KPS score of treatment group were better than these of control group .Conclusion Autologous BMSCs transplantation combined with HBO can promote the rehabilitation of neurologi-cal function and improve the living quality of patients with HCH .

关键词

骨髓间充质干细胞/高压氧/高血压脑出血

Key words

Bone marrow mesenchymal stem cells/Hyperbaric oxygen/Hypertensive cerebral hemorrhage

分类

医药卫生

引用本文复制引用

张化明,杨冰..自体骨髓间充质干细胞移植辅助高压氧治疗高血压脑出血临床观察[J].中国实用神经疾病杂志,2014,(21):15-17,3.

中国实用神经疾病杂志

1673-5110

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