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依达拉奉辅助治疗急性脑梗死60例临床观察

刘琴 方岩 徐辉

中国实用神经疾病杂志Issue(22):33-34,2.
中国实用神经疾病杂志Issue(22):33-34,2.

依达拉奉辅助治疗急性脑梗死60例临床观察

Clinical observation of 60 cases of acute cerebral infarction with edaravone adjuvant treatment

刘琴 1方岩 1徐辉1

作者信息

  • 1. 河南商丘市第一人民医院神经内科 商丘 476100
  • 折叠

摘要

Abstract

Objective to investigate the clinical efficacy and safety profile of edaravone adjuvant treatment on the acute cer-ebral infarction.Methods 120 cases with acute cerebral infarction were divided into the treatment group and the control group randomly ,each with 60 patients. Both groups were treated with conventional approach.Further ,the treatment group was in-travenously given edaravone 30mg ,2 times a day ,for a total of 14 days ,while the control group was given?physiological sa-line correspondingly.The difference in neurological defects as well as clinical efficacies was evaluated between before treatment and 48 hours ,1 week ,2 weeks after treatment.Results as determined by NIHSS ,neurological deficit score of the treatment group in 1 week or 2 weeks was significantly lower than the control group (P<0.05) ,though no significance observed in 48 hours. The clinical efficacy of the treatment group was not significantly better than the control group until 2 weeks (P<0.05).Conclusion Compared with conventional therapy alone ,edaravone adjuvant treatment of acute cerebral infarction has a good effect. Further ,no significant adverse reactions were observed.

关键词

依达拉奉/急性脑梗死/辅助治疗

Key words

Edaravone/Acute cerebral infarction/Adjuvant treatment

分类

医药卫生

引用本文复制引用

刘琴,方岩,徐辉..依达拉奉辅助治疗急性脑梗死60例临床观察[J].中国实用神经疾病杂志,2014,(22):33-34,2.

中国实用神经疾病杂志

1673-5110

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