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短程甲基强的松冲击疗法加干扰素治疗小儿病毒性脑炎

梁跃波 冉敏 蒲向阳

中国实用神经疾病杂志Issue(5):36-37,2.
中国实用神经疾病杂志Issue(5):36-37,2.

短程甲基强的松冲击疗法加干扰素治疗小儿病毒性脑炎

Curative efficacy of short-haul methylprednisolone pulse therapy loaded with interferon in the treatment of pe-diatric viral encephalitis

梁跃波 1冉敏 1蒲向阳1

作者信息

  • 1. 重庆市黔江中心医院儿科 重庆 409000
  • 折叠

摘要

Abstract

Objective To observe the effect of short methylprednisolone pulse therapy combined with interferon in the treatment of pediatric viral encephalitis .Methods 34 cases of children with viral encephalitis were selected and were randomly divided into two groups:the control group(n=15) and the observation group(n=19) .The control group was treated with in‐terferon treatment ,and the observation group was treated with methylprednisolone pulse therapy loaded with interferon treat‐ment .The time of the clinical symptoms improvement and differences of efficacy between the two groups were compared .Re‐sults The time of fever ,convulsions ,meningeal irritation (Kernig sign ,Brudzinski sign) ,pathologic reflex(Babinski sign) , unconsciousness ,the recovery of intracranial hypertension were significantly shorter than the control group (P<0 .05) .The total efficiency rate in the observation group was up to 94 .74% ,which was significantly higher than 60 .00% of the control group ,and the inefficiency rate was significantly lower than the control group (P<0 .05) .Conclusion On the basis of inter‐feron treatment ,loaded with short methylprednisolone pulse therapy can effectively reduce the time of the clinical symptoms improvement and efficacy .

关键词

小儿病毒性脑炎/甲基强的松冲击疗法/干扰素

Key words

Children with viral encephalitis/Methylprednisolone pulse therapy/Interferon

分类

医药卫生

引用本文复制引用

梁跃波,冉敏,蒲向阳..短程甲基强的松冲击疗法加干扰素治疗小儿病毒性脑炎[J].中国实用神经疾病杂志,2015,(5):36-37,2.

中国实用神经疾病杂志

1673-5110

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