中国实用神经疾病杂志Issue(6)：22-24,3.
抑郁症患者应用无抽搐电休克治疗对患者血清脑源性神经营养因子的影响
Analysis of serum brain-derived neurotrophic factors for patients with depression treated with therapy without seizure electroconvulsive
张晓莉 1代中全 1范红2
作者信息
- 1. 四川遂宁市中心医院心理咨询科 遂宁 629000
- 2. 四川遂宁市民康医院 遂宁 629000
- 折叠
摘要
Abstract
Objective To investigate the effect of serum brain-derived neurotrophic factors for patients with depression treated with therapy without seizure electroconvulsive. Methods 160 cases with depression were classified by random number table method based on sequence number of hospital admission ,odd-numbered cases were regarded as study group receiving therapy of seizure electroconvulsive and escitalopram ,while even-numbered cases as control group with escitalopram treat-ment.Results BDNF levels ,HAMD scores ,HAMA scores ,CGI scores and cognitive function in two groups after treatment were significantly higher than that before therapy (P<0.05) ,which had no difference in two groups before treatment(P>0.05). The effective rate with 92.50% in study group was prior to 82.50% in control group (P<0.05). In addition ,cases in two groups had no adverse reactions such as sexual dysfunction. Conclusion Adopting therapy without seizure electroconvul-sive in patients with depression can effectively improve cognitive function ,considered as a safe and effective treatment ,which should be widely applied.关键词
抑郁症/血清脑源性神经营养因子/无抽搐电休克Key words
Depression/Serum brain-derived neurotrophic factor/Without seizure electroconvulsive分类
医药卫生引用本文复制引用
张晓莉,代中全,范红..抑郁症患者应用无抽搐电休克治疗对患者血清脑源性神经营养因子的影响[J].中国实用神经疾病杂志,2015,(6):22-24,3.
