中国实用神经疾病杂志Issue(11)：3-5,6,4.
缺血性脑血管病并脑微出血相关因素分析及认知功能临床研究
Clinical study on cognitive function and the related factors of patients with ischemic cerebral vascular disease complicated with cerebral microbleeds
刘军贤 1王志东 2黄润霞1
作者信息
- 1. 河北保定市第三中心医院内二科 保定 071051
- 2. 河北遵化市人民医院神经内科 遵化 064200
- 折叠
摘要
Abstract
Objective To analyze cognitive function and the related factors of patients with ischemic cerebral vascular dis‐ease (ICVD) complicated with cerebral microbleeds (CMBs). Methods 240 cases of ICVD patients were selected as the re‐search objects and were divided into CMBs group and non CMBs group according to whether complicated with CMBs. 62 pa‐tients and 178 patients were included respectively. Mini Mental State Examination (MMSE) and Montreal cognitive assessment scale (MoCA) were applied to evaluate and compare the cognitive function of the patients.Results The age and proportions of patients with hypertension ,leukoaraiosis(LA) ,lacunar Infarction (LI) ,a history of previous stroke in CMBs group were sig‐nificantly higher than those in non CMBs group (P<0.05). The age (OR=1.376) ,hypertension (OR=3.965) ,and LI (OR=3.562) were the risk factors for the incidence of ICVD patients complicated with CMBs (P< 0.05). The total score of MMSE ,the total score of MoCA score and the scores of visuospatial/executive ,attention ,delayed memory items of patients in CMBs group were significantly lower than those of the patients in non CMBs group (P<0.05). The total score of MMSE ,the total score of MoCA score and the scores of visuospatial/executive ,attention ,language ,delayed memory items of patients with CMBs involving the cortico subcortical areas were significantly lower than those without involving CMBs involving the cortico subcortical areas (P<0.05).Conclusion The incidence of ICVD complicated with CMBs is associated with many factors ,and can lead to significant cognitive impairment ,which may be related with the occurrences of CMBs lesion involving the cortico subcortical areas.关键词
缺血性脑血管病/脑微出血/相关因素/认知功能Key words
Ischemic cerebral vascular disease/Cerebral microbleeds/Related factors/Cognitive function分类
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刘军贤,王志东,黄润霞..缺血性脑血管病并脑微出血相关因素分析及认知功能临床研究[J].中国实用神经疾病杂志,2015,(11):3-5,6,4.
