中国实用神经疾病杂志Issue(15)：66-66,76,2.
纳洛酮联用门冬氨酸鸟氨酸治疗肝硬化所致肝性脑病效果观察
Observation of naloxone combined with ornithine aspartate in treatment of liver cirrhosis caused by hepatic en-cephalopathy
郑英兰 1范丽青 2杨婷1
作者信息
- 1. 山东青岛市中心医院消化内科 青岛 266042
- 2. 山东青岛市中心医疗集团 青岛 266042
- 折叠
摘要
Abstract
Objective To investigate clinical value of ornithine aspartate and naloxone combination therapy for liver cirrho‐sis caused by hepatic encephalopathy.Methods From January 2011 to September 2014 we treated 86 cases of hepatic encepha‐lopathy patients with cirrhosis. They were randomly divided into control group of 43 patients ,implementation of ornithine as‐partate treatment ,observation group 43 cases ,taking naloxone ornithine aspartate combination treatment ,the effect was ob‐served in both groups of patients.Results The total effective rate was 90.70% in the observation group ,which was signifi‐cantly higher than 72.09% of the control group (P<0.05);after treatment ,blood ammonia and liver function indicators were compared between the two groups ,the observation group was better than the control group (P<0.05).Conclusion For hepat‐ic encephalopathy caused by cirrhosis aspartate and ornithine naloxone combination therapy can restore blood ammonia levels and liver function ,improve clinical effect ,benefit long‐term prognosis ,which is worthy of promotion.关键词
门冬氨酸鸟氨酸/纳洛酮/肝性脑病Key words
Ornithine aspartate/Naloxone/Hepatic encephalopathy分类
医药卫生引用本文复制引用
郑英兰,范丽青,杨婷..纳洛酮联用门冬氨酸鸟氨酸治疗肝硬化所致肝性脑病效果观察[J].中国实用神经疾病杂志,2015,(15):66-66,76,2.
