癌变·畸变·突变Issue(4)：285-287,3.DOI:10.3969/j.issn.1004-616x.2014.04.010
鱼牡蛎生乳灵胶囊促进大鼠泌乳功能的实验研究
Function of Yu-mu-li-sheng-ru-ling capsule in facilitating milk secretion in rats
胡培丽 1梁怿 1林飞1
作者信息
- 1. 中国食品药品检定研究院，北京 100050
- 折叠
摘要
Abstract
To study the function of Yu-mu-li-sheng-ru-ling capsule in milk secretion in rats. METHODS:SD rats with overload lactation model were used. The pregnant rats were randomly divided into four groups,including test groups with different dosage (1 800,900,450 mg/kg) and negative control group. The mother rats were gavaged for 25 d continuously during lactation. Body weight of mother and baby rats,survival ratio of baby rats and breast tissue pathology examination of mother rats were evaluated. RESULTS:No significant differences were observed in body weight of treated mother rats. For 450 and 900 mg/kg groups,baby rat survival ratios were 89%-94%, average body weight was insignificantly increased compared with that in negative control group(P>0.05). For 1 800 mg/kg group,baby rat survival ratio was 100%,average body weight increased significantly during early and late stage of lactation (P<0.05). Increased milk in breast tissue,filled acinus cavities and expanded mammary gland tubes were obviously observed. CONCLUSION:At 10 times higher than clinical dosage (1 800 mg/kg),Sheng-ru-ling capsule could facilitate milk secretion in lactating rats,increase baby rat body weight and reduce malnutrition death.关键词
促进泌乳/超负荷哺乳/大鼠/鱼牡蛎生乳灵胶囊Key words
facilitating milk secretion/overload lactation/rat/Yu-mu-li-sheng-ru-ling capsule分类
医药卫生引用本文复制引用
胡培丽,梁怿,林飞..鱼牡蛎生乳灵胶囊促进大鼠泌乳功能的实验研究[J].癌变·畸变·突变,2014,(4):285-287,3.
