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稳定期COPD患者营养状况与血清脂联素、肺功能、CAT评分的关系

李玉群 梁贤球 何晟 林敏 康闪闪 肖桂华 魏立平

安徽医科大学学报Issue(7):969-972,4.
安徽医科大学学报Issue(7):969-972,4.

稳定期COPD患者营养状况与血清脂联素、肺功能、CAT评分的关系

Relationship between the level of serum adiponection,lung fuction, CAT scores and malnutrition in COPD

李玉群 1梁贤球 1何晟 1林敏 1康闪闪 1肖桂华 1魏立平1

作者信息

  • 1. 广州医科大学附属第三医院呼吸内科,广州 510150
  • 折叠

摘要

Abstract

Objective To explore the relationship between the level of serum adiponection, lung fuction, CAT scores and malnutrition in stable COPD patients. Methods Seventy-seven stable COPD patients who completed COPD assessment test( CAT) and forty healthy controls participated in the study. COPD patients were divided into two groups according to MNA-SF scores:49 cases in malnutrition group and 28 cases in eutrophic group. The serum adiponection was measured and pulmonary function teste was conducted. Results The level of the serum adiponec-tion in the control group was higher than those of the other two groups. The level of serum adiponection in the eu-trophic group was lower than those of the malnutrition group, but there was no statistical difference in three groups (P>0. 05). The levels of the FEV1,FVC, FEV1/FVC and FEV1%pred in the malnutrition group was lower than those of the eutrophic group with a significant difference ( P<0. 01 ) . The CAT scores in the malnutrition group were significantly lower than those of the eutrophic group ( P<0. 01 ) . MNA-SF scores showed a positive correlation with FEV1,FVC,FEV1/FVC and FEV1%pred,a significant inversely correlation was observed between MNA-SF scores and CAT scores, serum adiponection was not significantly correlated with MNA-SF scores. Conclusion The malnutrition of COPD patients in stable stage has a significant correlation with their FEV1, FVC, FEV1/FVC, FEV1%pred and clinical symptoms. To improve the nutrition states of COPD patients in stable stage is helpful for their prognosis and quality of life. But the relationship between adiponection and malnutrition of COPD patients has not been demonstrated.

关键词

COPD/营养不良/脂联素浓度/肺功能/CAT/MNA-SF

Key words

COPD/malnutrition/serum adiponection/lung fuction/CAT/MNA-SF

分类

医药卫生

引用本文复制引用

李玉群,梁贤球,何晟,林敏,康闪闪,肖桂华,魏立平..稳定期COPD患者营养状况与血清脂联素、肺功能、CAT评分的关系[J].安徽医科大学学报,2014,(7):969-972,4.

基金项目

广东省科技计划项目(编号:63090) (编号:63090)

安徽医科大学学报

OA北大核心CSTPCD

1000-1492

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