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VATS治疗高龄早期非小细胞肺癌患者术后生活质量与开放手术的对比研究

张安庆 徐美青 解明然 梅新宇 马冬春 魏大中

安徽医科大学学报Issue(10):1460-1464,5.
安徽医科大学学报Issue(10):1460-1464,5.

VATS治疗高龄早期非小细胞肺癌患者术后生活质量与开放手术的对比研究

Comparison of the short-term quality of life in old patients with non-small cell lung cancer after lobectomy via video-assisted thoracoscopic or open surgery

张安庆 1徐美青 1解明然 1梅新宇 1马冬春 1魏大中1

作者信息

  • 1. 安徽省肿瘤医院 安徽省立医院西区 胸外科,合肥230031
  • 折叠

摘要

Abstract

Objective To compare the short-term quality of life in old patients( over 70 years) with non-small cell lung cancer underwent lobectomy via video-assisted thoracoscopic surgery(VATS) or open surgery. MethodsRetrospectively analyzed the medical records of 118 patients( over 70 year) underwent surgery who were pathologi-cally dignosed with pT1-2N0M0 non-small cell lung cancer. Among these, Sixty-three patients followed VATS (VATS group) and 55 patients followed open surgery (open group). The EORTC core questionnaire (QLQ LC-43) was applied to assess the short-term QOL of the patients before and 2, 4,12, 24 weeks after operation. Results The 2 groups were similar in terms of age, sex, tumor location, staging,incidence of comorbidities,in-hospital mortality and total morbidity. The VATS group was associated with a significant decrease in surgical blood loss, chest tube duration and postoperative stay relative to the open group(P<0.05). All of the global quality scale, functioning scale, general symptom scales ( or items) did not show differences before operation between the two groups. Further, the scores of global quality and physical functioning were higher in VATS group than in open group overall after operation, however, the scores of fatigue, pain, and pain in arm or shoulder were lower inverse-ly(P<0. 05). Conclusion Compared with open surgery,VATS shows an overall benefit on QOL for the patients with NSCLC during the follow-up of six month after lobectomy.

关键词

非小细胞肺癌/电视胸腔镜手术/生活质量

Key words

non-small cell lung cancer/video-assisted thoracoscopic surgery/quality of life

分类

医药卫生

引用本文复制引用

张安庆,徐美青,解明然,梅新宇,马冬春,魏大中..VATS治疗高龄早期非小细胞肺癌患者术后生活质量与开放手术的对比研究[J].安徽医科大学学报,2014,(10):1460-1464,5.

基金项目

安徽省卫生厅科技课题(编号:13zc021) (编号:13zc021)

安徽医科大学学报

OA北大核心CSTPCD

1000-1492

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