安徽医科大学学报Issue(10)：1479-1481,1501,4.
脓毒症患者预后危险因素的Logistic回归分析
Logistic regression analysis of the prognostic factors of patients with sepsis
摘要
Abstract
Objective To investigate the prognostic factors in patients with sepsis and to provide the theoretical basis for clinical diagnosis and treatment. Methods A total of 141 septic patients were analyzed retrospectively. Patients were divided into two groups:those who were alive at time of ICU discharge ( survivors;n=83 ) and those who died or to give up before terminal stage ( nonsurvivors;n=58 ) . Then the clinical data were statistically ana-lyzed. Results In the death group: age, APACHE II score, blood urea nitrogen, serum creatinine, C-reactive protein were significantly higher than the survival group (P<0. 01) while albumin, pre albumin were lower than that in the survival group (P<0.01). The Logistic regression analysis illustrated: age ( > 60 years), APACHEIIscore ( >20 score) and blood urea nitrogen ( > 9 mmol/L) , serum creatinine ( > 176 μmol/L) , C-reactive protein level were independent predictors of death in patients with sepsis ( P<0 . 05 ) . Then drew the receiver oper-ating characteristic curve ( ROC curve) and analyzed the respective risk factor for predicting prognosis value of sep-sis with the help of ROC curve. Conclusion Age, high APACHE II score in early sepsis, increased urea nitro-gen, elevated serum creatinine and increased C-reactive protein levels were regarded as prognostic value indicators for adverse clinical outcomes in patients with sepsis.关键词
脓毒症/预后/危险因素/Logistic回归Key words
sepsis/prognosis/risk factors/Logistic regression分类
医药卫生引用本文复制引用
范泉,张泓..脓毒症患者预后危险因素的Logistic回归分析[J].安徽医科大学学报,2014,(10):1479-1481,1501,4.基金项目
安徽省自然基金项目(编号:1208085MH150) （编号:1208085MH150）
