安徽医科大学学报Issue(1)：119-121,3.
不同时间窗应用替罗非班对PCI术中无复流的疗效观察
Effects of tirofeban administrated at various time points on no-reflow phenomenon during PCI
摘要
Abstract
128 patients who had no-reflow due to acute thrombosis during PCI were selected. Patients were random-ized into two groups with 64 cases in each group. All people bolus loading tirofiban in coronory artery. Group A:Tirofeban was injected via guiding catheter when TIMI grade was≥1 after passing-through of guidewire,balloon or pre-dilatation of balloon, or injection via microcatheter when there was no antegrade flow after aforementioned man-agement;Group B:Tirofeban was directly injected via guiding catheter when no-reflow occurred. Immediate blood flow in target vessel after PCI, improvement of symptoms 3 days after procedure as well as 30-day major adverse cardiovascular events ( MACE) were assessed. Results were that intraprocedural blood flow recovery and symptom improvement 3 days after procedure were better in Group A than in Group B with statistical significance ( P <0. 05 );the incidence of 30-day MACE was lower in Group A than that in Group B with statistical significance ( P<0. 05). The methods of group A may reverse no-reflow,reduce symptomatic discomfort as well as lower short-term MACE incidence more than group B.关键词
急性冠脉综合征/替罗非班/无复流/PCIKey words
acute coronary syndrome/tirofeban/no-reflow/percutaneous coronary intervention分类
医药卫生引用本文复制引用
李超,程自平,陈刚,赵韧,胡茜茹,赵宇飞..不同时间窗应用替罗非班对PCI术中无复流的疗效观察[J].安徽医科大学学报,2015,(1):119-121,3.基金项目
安徽省高校省级自然科学研究重点项目(编号:KJ2014A122) （编号:KJ2014A122）
