安徽医科大学学报Issue(2)：223-226,4.
射频消融术对心肌病阵发性心房颤动患者心脏逆重构的影响
The effect of radiofrequency catheter ablation on cardiac reverse remodeling in cardiomyopathy patients with paroxysmal atrial fibrillation
摘要
Abstract
Objective To explore the effect of radiofrequency catheter ablation( RFCA) on cardiac reverse remode-ling and improvement of life quality in cardiomyopathy patients with paroxysmal atrial fibrillation( PAF) . Methods 95 cardiomyopathy patients with PAF were enrolled in our study and divided into two groups. RFCA group:62 patients received circumferential pulmonary vein isolation, ( left ventricular end-diastolic ) LVEDD ≥55 mm (male), LVEDD ≥50 mm (female); Drug group:33 patients were treated with drug for controlling heart rate ( resting heart rate around 60~80 bpm, heart rate during daily activity <100 bpm) . 72 hours after admission or 6 months after surgery in RFCA group, when the heart rate returned to normal or 6 months after treatment in Drug group, Short-Form36(SF-36) was used to evaluate the quality of living in the patients respectively; transthoracic echocardiography was performed in sinus rhythm;LAD, LVEDD and LVEF of the patients were measured. Results in RFCA group, LAD and LVEDD of 62 patients reduced and LVEF increased in 6 months after surgery statisti-cally significant(P<0. 05). In Drug group, 6 months after treatment, LAD and LVEDD of 33 patients increased ( P<0. 05 ) , without significant change in LVEF. There was no statistical significance in psychological health, physical function and general health perceptions, but there was significant improvement in social function and phys-ical function,affective state, physical role and energy in both RFCA group and drug group (P<0. 05), and it was more obvious in RFCA group(P<0. 05). Conclusion RFCA can reverse cardiac structural remodeling via sinus rhythm maintenance and improve the quality of life in cardiomyopathy patients with PAF.关键词
心房颤动/射频消融术/心肌病/逆重构Key words
atrial fibrillation/radiofrequency ablation/cardiomyopathy/reverse remodeling分类
医药卫生引用本文复制引用
刘飞,徐健,严激..射频消融术对心肌病阵发性心房颤动患者心脏逆重构的影响[J].安徽医科大学学报,2015,(2):223-226,4.基金项目
安徽省科技攻关项目基金(编号:1301042210) （编号:1301042210）
