安徽医科大学学报Issue(3)：352-356,5.
甲状旁腺CT三维重组对难治性继发性甲状旁腺功能亢进症的术前诊断意义和生化相关性研究
Preoperative diagnostic significance of 3 D-reconstructed CT and biochemical correlation study of parathyroid in refractory secondary hyperparathyroidism
摘要
Abstract
Objective To investigate the application value of 3 D-reconstructed CT of parathyroid in preoperative diagnosis and evaluation of refractory secondary hyperparathyroidism ( SHPT) and analyze the correlation between the volume of parathyroid hyperplasia and main biochemical indicators. Methods Forty-eight cases of patients di-agnosed with SHPT underwent 3D-reconstructed CT of parathyroid prior to surgery. A control study was performed based on test results and postoperative pathological results for analysis of their consistency and CT-based detection rate, as well as the correlation between the volume of parathyroid hyperplasia and serum inorganic phosphorus or parathyroid hormone (PTH). Results The detection positive rate of parathyroid hyperplasia by 3D-reconstructed CT was 92. 9% (172/185). The difference in the detection rate between bilateral posterior thyroid lobes was not statistically significant. The volume of parathyroid hyperplasia measured by CT showed a significant positive correla-tion to preoperative serum inorganic phosphorus and PTH value. Conclusion 3D-reconstructed CT has a high de-tection rate of parathyroid hyperplasia for patients with refractory secondary hyperparathyroidism, which can clearly display the relationship between anatomical location of the lesion and its adjacent structures. Combined with related biochemical examinations, it can better reflect the severity of patient's condition, thus playing a crucial role in pre-operative clinical diagnosis and evaluation of parathyroid hyperplasia.关键词
CT/继发性甲状旁腺功能亢进症/诊断/生物化学Key words
CT/secondary hyperparathyroidism/diagnosis/biochemistry分类
医药卫生引用本文复制引用
徐佳玮,郑穗生,郝丽,姚文君..甲状旁腺CT三维重组对难治性继发性甲状旁腺功能亢进症的术前诊断意义和生化相关性研究[J].安徽医科大学学报,2015,(3):352-356,5.基金项目
安徽高校省级自然科学研究项目(编号:KJ2013Z155) （编号:KJ2013Z155）
