安徽医科大学学报Issue(5)：645-647,3.
乳腺癌化疗后抑郁情绪对其认知功能影响的研究
The impact of depression on chemotherapy induced cognitive impairment in breast cancer patients
摘要
Abstract
Objective To investigate the relationships of cognitive impairment and depression in postoperative breast cancer patients who had received chemotherapy. Methods Sixty-eight postoperative breast cancer patients without depression underwent self-rating depression scale and neuropsychological tests before the start of chemother-apy and after six cycles of standard treatment. Results The sixty-three breast cancer patients after chemotherapy performed significantly difference in self-rating depression scale,mini-mental state examination,delayed recall and digit span backward. As compared with non-depression group after chemotherapy,the correct numbers of mini-men-tal state examination, verbal fluency test, immediate recall,delayed recall and digit span backward were lower in the depression group. Conclusion There are total cognition and memory impairment in postoperative breast cancer patients with depression. The evidence suggests that depression maybe further aggravate chemotherapy induced cog-nitive impairment in postoperative breast cancer patients.关键词
抑郁/认知障碍/乳腺癌Key words
depression/cognitive impairment/breast cancer分类
医药卫生引用本文复制引用
杨明慧,程怀东,陈振东,黄忠连,王小磊..乳腺癌化疗后抑郁情绪对其认知功能影响的研究[J].安徽医科大学学报,2015,(5):645-647,3.基金项目
国家自然科学基金(编号:81372487) （编号:81372487）
