安徽医科大学学报Issue(5)：653-656,4.
RT-3DE 技术评价蒽环类药物对乳腺癌患者左室收缩同步性的影响
Left ventricular systolic synchrony in breast cancer patients receiving anthracycline using real-time three-dimensional echocardiography
摘要
Abstract
Objective To evaluate the left ventricular systolic speckle synchrony by RT-3DE in breast cancer pa-tients with different cardiac status receiving anthracycline. Methods 40 breast cancer patients were divided into normal group and cardiopathy group in 2 stages (before chemotherapy, after the sixth cycle of chemotherapy). 20 patients after surging without chemotherapy were as the control group. They all underwent RT-3DE examination. The QLAB software was used to analyze the data of left ventricular systolic synchrony and to obtain 17-segmental volume-time curves. Results Before chemotherapy, the three groups’ curves were regular parabola and arrange in order, and the data of left ventricular systolic synchrony were not different among the three groups(P > 0. 05). Af-ter the sixth cycle of chemotherapy, in the normal group and cardiopathy group the curves were interlace with each other, and parts of the data of left ventricular systolic synchrony were higher than those in the control group. They all increased significantly in the cardiopathy group (P < 0. 01). Conclusion The left ventricular systolic synchro-ny gets worse in breast cancer patients receiving anthracycline, which can be aggravated in cardiopathy group.关键词
三维/超声心动图/蒽环类/乳腺癌/收缩同步性Key words
three-dimensional/echocardiography/anthracycline/breast cancer/systolic synchrony分类
医药卫生引用本文复制引用
伍婷婷,姜凡,张新书,张博,卢业伟,方思华..RT-3DE 技术评价蒽环类药物对乳腺癌患者左室收缩同步性的影响[J].安徽医科大学学报,2015,(5):653-656,4.基金项目
国家自然科学基金(编号:81301771) （编号:81301771）
