安徽医科大学学报Issue(7)：1004-1007,4.
生长激素受体在宫腔粘连患者子宫内膜组织中的表达及意义
Expression and significance of growth hormone receptor in the endometrial tissue of intrauterine adhesion patients
摘要
Abstract
Objective To investigate the growth hormone receptor ( GHR) expression and significance of endome-trial tissue in patients with intrauterine adhesions. Methods Immunohistochemistry MaxVision twostep and quanti-tative real-time PCR ( qRT-PCR) were used to detect the expression of GHR protein and GHR mRNA IUA in pa-tients endometrial tissue of IUA group ( study group) and non IUA group ( control group) . Results Using immu-nohistochemistry assay to detect GHR protein expression and qRT-PCR to detect the GHR mRNA expression, and the differences between the study group and the control group were statistically significant(P<0. 05). Immunohis-tochemistry was used to detect the expression of GHR protein in endometrial glands and endometrial stromal, the difference between the two parts were statistically significant ( P<0. 05 ) . Conclusion The expression of GHR in endometrial tissue in patients with IUA is lower than those of non-IUA, and this expression is more in endometrial glands, less in endometrial stroma,which provide a theoretical reference for the use of hormone in IUA patients after transcervical resection of adhesions( TCRA) .关键词
宫腔粘连/生长激素/生长激素受体Key words
intrauterine adhesions/growth hormone/growth hormone receptor分类
医药卫生引用本文复制引用
任娟,卫兵,宋恩学,王文艳,张丽丽..生长激素受体在宫腔粘连患者子宫内膜组织中的表达及意义[J].安徽医科大学学报,2015,(7):1004-1007,4.基金项目
国家自然科学基金青年科学基金项目(编号:81100412) （编号:81100412）
