北京大学学报（医学版）Issue(2)：302-304,3.DOI:10.3969/j.issn.1671-167X.2015.02.022
椎基底动脉延长扩张症的计算流体力学分析
Analysis of vertebrobasilar dolichoectasia based on computational fluid dynamics
摘要
Abstract
Objective:To anslysis the hemodynamic states of vertebrobasilar dolichoectasia based on computational fluid dynamics technique.Methods:The original DICOM format image data from a patient with vertebrobasilar dolichoectasia (VBD), were imported by the Mimics software directly,and the 3D Objects were constructed.The simulation of model was made with Ansys software, the hemodynamic pa-rameters such as streamlines, wall shear stress( WSS) and wall pressure were described.Results:There was stable laminar flow in proximal basilar artery and was no blood flow mixed by bilateral vertebral arter-y.However, Spiral flows were appeared in distal tortuous basilar artery.The low WSS regions in the ver-tebra-basilar junction section and inferior segment of basilar artery were coincide with the high wall pres-sure regions.It could be speculated the initial growth regions might be located in the vertebra-basilar junction section and inferior segment of basilar artery.Local regions with low WSS and high wall pressure might be associated with the occurrence and development of VBD.Conclusion: CFD numerical simula-tion maybe can provide a theoretical basis for the role of hemodynamic factors in occurrence and develop-ment of VBD.关键词
椎基底动脉供血不足/计算流体力学/血流动力学Key words
Vertebrobasilar insufficiency/Hydrodynamics/Hemodynamics分类
医药卫生引用本文复制引用
韩金涛,乔惠婷,韩旭,李选,和清源,叶珊,栾景源,王昌明,董国祥..椎基底动脉延长扩张症的计算流体力学分析[J].北京大学学报（医学版）,2015,(2):302-304,3.基金项目
国家自然科学基金（81101123）资助Supported by Natural Science Foundation of China （）
