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脉冲动态核极化增强的NMR和MRI系统研究

贺玉贵 刘朝阳 冯继文 张志 王超 倪胜 胡少斌 王东 陈方 刘买利

波谱学杂志Issue(2):393-398,6.
波谱学杂志Issue(2):393-398,6.DOI:10.11938/cjmr20150221

脉冲动态核极化增强的NMR和MRI系统研究

Development of Pulsed Dynamic Nuclear Polarization for Enhancing NMR and MRI

贺玉贵 1刘朝阳 2冯继文 1张志 1王超 1倪胜 3胡少斌 1王东 3陈方 1刘买利1

作者信息

  • 1. 波谱与原子分子物理国家重点实验室,武汉磁共振中心 中国科学院 武汉物理与数学研究所,武汉 430071
  • 2. 武汉光电国家实验室筹,华中科技大学光学与电子信息学院,武汉430074
  • 3. 中国科学院大学,北京 100049
  • 折叠

摘要

Abstract

In this report, we present a pulsed dynamic nuclear polarization (DNP) system, being reconfigurable for DNP enhanced magnetic resonance imaging (DNP-MRI) and magnetic resonance spectroscopy (DNP-MRS). Several novel console designs are proposed in the presented DNP system. A distributed digital architecture based on Peripheral Component Interconnect Express (PCIe) has been developed, so as to significantly improve the efficiency of data transmission and communication reliability as well as the precise control of pulse sequence. An external high speed Double Data Rate (DDR) memory chip is used for storing FID data and pulse sequence elements, greatly speeding up the execution of the pulse sequence and reducing the interval of TR and improving the accuracy of TR in image sequence. Using clock phase-shift technology, we can produce digital pulse accurately with high timing resolution of nanosecond timescales. Finally, two experimental examples for DNP-MRS and DNP-MRI are shown.

关键词

核磁共振(NMR)/磁共振成像(MRI)/脉冲动态核极化/控制台/PCIe

Key words

NMR/MRI/pulsed DNP/console/PCIe

分类

数理科学

引用本文复制引用

贺玉贵,刘朝阳,冯继文,张志,王超,倪胜,胡少斌,王东,陈方,刘买利..脉冲动态核极化增强的NMR和MRI系统研究[J].波谱学杂志,2015,(2):393-398,6.

基金项目

Grant from the special equipment of scientific instrument of Chinese Academy of Sciences, the Ministry of Science and Technology of China (2011YQ120035) and the National Natural Science Foundation of China (11405264) (2011YQ120035)

波谱学杂志

OA北大核心CSCDCSTPCD

1000-4556

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