滨州医学院学报Issue(5)：357-360,4.
睡眠剥夺对大鼠不同脑区 syp 表达的影响
Effect of sleep deprivation on the expression of syp in different brain area of rats
赵光涛 1胡西壮 1王龙飞 1李滨1
作者信息
- 1. 滨州医学院人体解剖学实验室 烟台 264003
- 折叠
摘要
Abstract
Objective To investigate the effects of sleep deprivation on the expression of SYP in different brain area of rats . Methods 20 sprague dawley rats were randomly divided into control group (n=10) ,model group (n=10) .Sleep deprivation models were established by the modified multiple platform methods ,5 control group rats and 5 sleep deprivation model group rats were randomly selected and sacrificed at 24 hours .The other rats were sacrificed at 72 hours .The expression levels of syp in different region of brain were detected by immunohistochemical .The control group rats were left intact .Results The expres‐sion of syp in hippocampus and prefrontal cortex in model group were much higher than that of control group ,but there was no difference in the expression of syp in corpus striatum of the two groups .Conclusion Sleep deprivation could decrease the ex‐pression of syp in hippocampus and prefrontal cortex ,but had no effect on the expression of syp in corpus striatum .关键词
睡眠剥夺/syp/前额叶皮质/海马/纹状体Key words
sleep deprivation/syp/prefrontal cortex/hippocampus/corpus striatum分类
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赵光涛,胡西壮,王龙飞,李滨..睡眠剥夺对大鼠不同脑区 syp 表达的影响[J].滨州医学院学报,2014,(5):357-360,4.
