川北医学院学报Issue(5)：474-478,5.DOI:10.3969/j.issn.1005-3697.2014.05.16
3.0 T磁共振波谱成像结合T2 WI对前列腺癌与前列腺增生的鉴别诊断价值
The value of 3 . 0 T magnetic resonance spectroscopy with T2 WI in the dif-ferential diagnosis between prostate cancer and benign prostatic hyperplasia
摘要
Abstract
Objective:To investigate the value of 3. 0T magnetic resonance spectroscopy with T2 WI in the differential diagnosis be-tween prostate cancer(PCa)and benign prostatic hyperplasia(BPH). Methods:Retrospectively analyses MRI data of 49 patients with prostate diseases confirmed by transrectal ultrasound-guided needle biopsy. 27 patients were PCa and 22 patients were BPH. All patients were performed traditional MRI(T2WI)and magnetic resonance spectroscopy(MRS). T2WI sequence observation was focused on the size and shape of the prostate gland,the location of the lesion,the signal features and the extent of the tumor. Select voxels according to the pathologic results,MRS findings were measured the metabolic concentration of citrate(Cit),choline(Cho)and creatine(Cre),and the ratio of( Cho+Cre)/Cit. The ratio of( Cho+Cre)/Cit were compared between the groups PCa and BPH by using independent sam-ples t-test. Results:On T2 WI,18 cases had apparent sign of PCa among 22 cases. The affected adjacent structures included bladder( n=4),seminal vesicle(n=12),rectum(n=4),pelvic lymph nodes fused in mass(n=8)and bone of pelvic(n=11). 4 cases had no apparent sign of PCa. All cases had apparent sign in BPH. On MRS,138 voxels were selected in PCa,Cit peak was apparently declined and Cho peak was obviously ascended. Oppositely,132 voxels were selected in BPH,Cit peak was obviously higher than Cho and Cre. The average ratio of(Cho+Cre)/Cit for PCa was 2. 05 ± 0. 61. While,in BPH,the average ratio of(Cho+Cre)/Cit was 0. 53 ± 0. 19. Independent samples t-test shows that their differences between PCa and BPH were statistically significant(t= -27. 241,P<0. 05). Conclusion:MRS and T2 WI can offer effective diagnosis and differential diagnosis between PCa and BPH,which had higher value of clinical application.关键词
磁共振波谱/磁共振成像/前列腺癌/前列腺增生Key words
Magnetic resonance spectroscopy( MRS)/Magnetic resonance imaging( MRI)/Prostate cancer( PCa)/Benign prostatic hyperplasia( BPH)分类
医药卫生引用本文复制引用
刘兴华,曾文兵,汪明全,温云,王怀武..3.0 T磁共振波谱成像结合T2 WI对前列腺癌与前列腺增生的鉴别诊断价值[J].川北医学院学报,2014,(5):474-478,5.基金项目
重庆市万州区科委项目(201203042) （201203042）
