川北医学院学报Issue(2)：147-150,4.DOI:10.3969/j.issn.1005-3697.2015.02.04
特发性血小板减少性紫癜合并急性心肌梗死患者血小板参数变化的临床意义
The variations and clinical significance of platelet parameters in idiopathic thrombocytopenic purpura patients accompanied with acute myocardial in-farction
摘要
Abstract
Objective:To investigate the variation of platelet parameters and its clinical significance in idiopathic thrombocyto-penic purpura patients and acute myocardial infarction ( AMI) before and after the occurrence of AMI. Methods:11 cases of patients with idiopathic thrombocytopenic purpura patients and acute myocardial infarction( ITP&AMI) ,30 cases of patients with acute myocar-dial infarction were diagnosed by CAG (AMI),30 cases of patients with idiopathic thrombocytopenic purpura (ITP),40 healthy people were included as control subject. Before and after treatment, 5 platelet parameters [ platelet count ( PLT ) , mean platelet volume ( MPV) ,platelet distribution width ( PDW) and platelet-large cell ratio ( P-LCR) and immature platelet fraction ( IPF) were detected in all cases;meanwhile,the detection results before and after treatment were compared and statistically analyzed with healthy controls. Results:Before treatment,MPV,PDW,P-LCR and PLT were statistically significant in ITP&AMI group and AMI group,IPF has no statistical significance(P>0. 05);P-LCR,PDW and IPF was statistically significant (P<0. 05) in ITP&AMI group and ITP group,PLT and MPV have no statistical significance(P>0. 05);MPV,PDW,P-LCR and PLT were statistically significant in ITP group and AMI group,IPF have no statistical significance;MPV,PDW,P-LCR,PLT and IPF were statistically significant in ITP&AMI group and ITP group control with the control;MPV,PDW,PLT and IPF were statistically significant(P<0. 01)in AMI group and the control,P-LCR has no statistical significance. PLT, P-LCR,PDW and IPF in ITP&AMI group of after treatment were statistically significant with the before (P<0. 01),there was no significant difference in MPV(P>0. 05);MPV,PDW,P-LCR,PLT and IPF in ITP group and AMI group of after treatment were statistically significant with the before. Conclusion:The platelet parameters could provide the important clinical information about treatment and prognosis of idiopathic thrombocytopenic purpura patients with acute myocardial infarction.关键词
急性心肌梗死/免疫性血小板减少性紫癜/血小板参数Key words
Acute myocardial infarction/Idiopathic thrombocytopenic purpura/Platelet parameters分类
医药卫生引用本文复制引用
徐楠楠,宋书凯,马东方,李敬田,吕孝欣,李双宏,张立辉..特发性血小板减少性紫癜合并急性心肌梗死患者血小板参数变化的临床意义[J].川北医学院学报,2015,(2):147-150,4.基金项目
潍坊市科学技术发展计划项目(2014WS006) （2014WS006）
