川北医学院学报Issue(2)：255-259,5.DOI:10.3969/j.issn.1005-3697.2015.02.33
泛素蛋白酶体系统在Wnt通路中的研究进展
The research on the ubiquitin proteasome system in Wnt signal pathway
摘要
Abstract
Wnt signal pathway is a complex system involved by a variety of molecular which are influenced,restricted and syn-ergied by each other. It is related with the cell signal transduction,cell cycle,cell proliferation,migration and differentiation,apoptosis, adhesion and the potential differentiation ability of stem cells. Ubiquitin proteasome system plays an important role in cell activity through regulated the protein activity,subcellular localization,protein interaction,et al. The key moleculars in Wnt signal pathway,such as β-catenin,is closely regulated by ubiquitin proteasome system. The purpose of this paper is to elaborate the relationship of the Wnt signal pathway with the ubiquitin proteasome system.关键词
泛素蛋白酶/Wnt/E3连接酶/β-cateninKey words
Ubiquitin proteasome system/Wnt/E3 Ligase/β-catenin分类
医药卫生引用本文复制引用
朱剑军,朱晓华,黄平,蒋辉,邓世山..泛素蛋白酶体系统在Wnt通路中的研究进展[J].川北医学院学报,2015,(2):255-259,5.基金项目
四川省教育厅基金项目(13ZB0242) （13ZB0242）
四川省科技厅项目(2012ZZ008) （2012ZZ008）
