川北医学院学报Issue(4)：494-497,4.DOI:10.3969/j.issn.1005-3697.2015.04.19
羟考酮联合氟比洛芬酯用于骨科术后镇痛中的效果研究
Effect of postoperative analgesia in orthopedic oxycodone for joint flurbi-profen
摘要
Abstract
Objective:To analyze the oxycodone combined flurbiprofen for postoperative analgesia in orthopedic clinical efficacy and safety in clinical studies to provide analgesia for orthopedic surgery. Methods:From April 2013 to May 2014 during orthopedic sur-gery,80 patients,according to the analgesic method used will be divided into a control group and the experimental group,40 cases,each group of patients in the experimental group connected oxycodone ketone combined with flurbiprofen analgesia analgesia ( oxycodone hydrochloride 50mg+250mg+saline flurbiprofen to 100 mL),patients in the control group connected Dezocine joint flurbiprofen anal-gesia(Dezocine flurbiprofen 25 mg+250mg+saline to 100mL). Were observed in patients with postoperative pain VAS,BCS and Ram-say score differences;analyze the differences in the two groups of patients overall satisfaction;relatively poor condition of postoperative sedation reactions. Results:The experimental group were killed 1h,3h,5h,VAS 7h time,BCS score significantly higher,the difference was statistically significant(P<0. 05)between the two groups,after 12h,24h and 48h,VAS,BCS score and the control group showed no significant difference(P>0. 05);patients in the experimental group 1h,3h,5h,7h,12h,Ramsay score difference compared with the control group,24h and 48h,no significant(P>0. 05);the experimental group were grade I,II level patient satisfaction rate was higher (P<0. 05),III level,IV-class patient satisfaction rate than the control group(P<0. 05);The postoperative sedation dizziness occur,nausea,vomiting,pruritus, respiratory disorders, as well as the incidence of other adverse events was no significant difference ( P >0. 05). Conclusion:Oxycodone joint flurbiprofen for orthopedic postoperative analgesia,can significantly improve the patient’s VAS, BCS score significantly improve patients’ overall satisfaction with analgesia,safe and reliable,is a worthy use in clinical practice orthope-dic postoperative analgesia.关键词
羟考酮/氟比洛芬酯/评分/满意度/不良反应Key words
Oxycodone/Flurbiprofen/Rating/Satisfaction/Adverse reactions分类
医药卫生引用本文复制引用
祖翠华..羟考酮联合氟比洛芬酯用于骨科术后镇痛中的效果研究[J].川北医学院学报,2015,(4):494-497,4.基金项目
徐州市卫生局资助基金(20182345) （20182345）
