摘要
Abstract
Objective:To evaluate the MRI appearance of phyllodes breast tumors and to differentiate them from ifbroadenomas. Materials and Methods:MR images were obtained on GE medical system 3.0-T imager. MR images of 23 patients with 24 phyllodes breast tumors proved by surgery or biopsy pathology were retrospectively analyzed. The results were compared with the MRI appearance of 62 ifbroadenomas of 59 patients by using Chi-square test Fisher’s Exact test and t test. Results:There is statistical difference (P=0.004) in average maximum diameter between phyllodes breast tumor and ifbroadenomas. Still, there is another statistical difference (P<0.05) in tumor shape and edge between the both. Phyllodes tumors show as lobulated shape commonly (12/24, 50.00%) or irregular shape sometimes (2/24, 8.33%), while ifbroadenomas show as quasi-circular shape (29/62, 46.77%) or lobulated shape (27/62, 43.55%) commonly and no irregular shape seen. In the aspects of tumor edge, most ifbroadenomas show smoothly (58/62, 93.55%) and less irregular edge. On the contrary, phyllodes tumors have more irregular edges (7 tumors with irregular edges (29.17%) and 1 tumor with spiculation). Meanwhile, 11 (11/24, 45.83%) phyllodes tumors show patchy hyperintense (bleeding tip) on T1WI compared with ifbroadenomas, which has no this kind of signal. On T2WI fat saturation, it shows statistical difference (P=0.025) that phyllodes tumors have hyperintense mostly (21/24, 87.5%) with no isointense or hypointense and fibroadenomas have isointense, hypointense and mixed signal as well as hyperintense (43/62, 69.35%). Furthermore, cystic change area is to be seen in 8 (8/24, 33.33%) phyllodes tumors and no this kind of area in ifbroadenomas. In terms of enhanced low signal lace and no-enhanced one, both tumors have not evidently statistical difference. Regarding of curve characteristic, the statistical difference (P=0.008) has showed that II type and III type is mostly seen in phyllodes tumors I type is seen at most in ifbroadenomas. Finally, there is no evidently statistical difference (P=0.068) of average ADC between both tumors. Conclusions:There are differences between the phyllodes breast tumors and ifbroadenomas on MRI performance. Several DCE-MR ifndings can be used to help differentiation of phyllodes breast tumors from ifbroadenomas.关键词
乳腺肿瘤/叶状肿瘤/纤维腺瘤/磁共振成像/诊断,鉴别Key words
Breast neoplasms/Phyllodes tumor/Fibroadenoma/Magnetic resonance imaging/Diagnosis, differential分类
医药卫生
