磁共振成像Issue(2)：131-135,5.DOI:10.3969/j.issn.1674-8034.2015.02.010
MR扩散加权成像表观扩散系数与乳腺浸润性导管癌病理分级相关性研究
Correlations between apparent diffusion coefifcient values and histopathologic classiifcation of breast invasive ductal carcinoma
摘要
Abstract
AbstractObjectives:The aim of this study was to evaluate the correlation between apparent diffusion coefficient (ADC) values and histopathologic classification of breast invasive ductal cancer.Materials and Methods:Sixty-six cases of breast cancer conformed by histopathology with histopathologic classiifcation were involved in this retrospective study. The ADC values of lesions were measured and the mean (ADCmean) and minimum (ADCmin) of regions of interest (ROIs) were taken. The cases were divided into two groups, histopathologic classification and prognostic recurrence, according to the treatment and prognosis (histopathologic classification, lymph node status). The correlation was analyzed by using SPSS19.0 software (one-way ANOVA, LSD test andSpearman’ rank correlation coefifcient method).Results:There were two groups, histopathologic classiifcation group and prognostic recurrence group, which were divided three stages, respectively. ADCmean were 0.993×10-3 mm2/s、0.969×10-3mm2/s、0.926×10-3mm2/s, respectively, whileADCmin were0.849×10-3 mm2/s、0.660×10-3 mm2/s、0.535×10-3 mm2/s in the former group, respectively, ADCmean were1.014×10-3 mm2/s、1.029×10-3 mm2/s、0.919×10-3 mm2/s, respectively, while ADCmin were 0.918×10-3 mm2/s、0.750×10-3 mm2/s、0.540×10-3 mm2/s in the latter group, respectively. ADCmean had no correlation with either histopathologic classification group or prognostic recurrence group. There was negative correlation between ADCmin and histopathologic classification group (r=-0.615,P=0.000) as well as prognostic recurrence group (r=-0.754,P=0.000).Conclusions:The ADCmin <br> can be considered as an indicator of the development of medical plan before breast cancer surgery and the preliminary assessment of prognostic recurrence.关键词
乳腺癌/病理分级/表观扩散系数Key words
Breast cancer/Histopathologic classiifcation/Apparent diffusion coefifcient分类
医药卫生引用本文复制引用
张卫,苏丹柯,罗宁斌,金观桥,谢东,韦苇,黄向阳,康巍..MR扩散加权成像表观扩散系数与乳腺浸润性导管癌病理分级相关性研究[J].磁共振成像,2015,(2):131-135,5.基金项目
广西科学研究与技术开发计划项目(编号桂科攻14124004-1-11)；广西壮族自治区卫生厅自筹经费科研课题项目(编号Z2013418) （编号桂科攻14124004-1-11）
