磁共振成像Issue(4)：253-257,5.DOI:10.3969/j.issn.1674-8034.2015.04.003
磁共振弥散张量成像技术在新生儿脑白质发育中的研究
Diffusion tensor imaging study of normal neonatal brain maturation
摘要
Abstract
Objective:The purpose of this study was to investigate the developing status and characteristics of cerebral white matter during the neonatal period by using diffusion tensor imaging technique. Materials and Methods:In this study, 38 newborns were selected, including eighteen preterm infants (appropriate for gestational age) and twenty term infants (normal birth weight), they were divided into three groups according to their gestational age, fractional anisotropy obtained from each region of interest was analyzed. Results:The differences of FA values between left and right hemispheric white matter regions were no signiifcant statistically. FA values for the peripheral white matter regions were lower than the values for deep white matter structures,in the deep white matter, the splenium of corpus callosum showed larger FA than genu, and the anterior limb of internal capsule showed smaller FA than posterior limb of internal capsule, the FA values for the splenium were higher than the values for the posterior limb of internal capsule. Among peripheral white matter, FA in central white matter (the level of central semiovale) were the highest, no signiifcant differences were observed between anterior and posterior white matter (the level of central semiovale) (all P>0.05). FA values for all measured regions in groupⅢwere more than that values in groupⅠ, and the differences were signiifcant statistically (all P<0.05), comparison between adjacent groups, there were signiifcant statistically only in part of regions of interest. Conclusion:Diffusion tensor imaging technique is very usefull in the study of neonatal white matter maturation, FA value can assess myelin development quantitatively.关键词
新生儿/脑/髓鞘/弥散磁共振成像Key words
Neonate/Brain/Myelin sheath/Diffusion magnetic resonance imaging分类
医药卫生引用本文复制引用
刘岭岭,孛茹婷,杨文君,李艳,田淑萍,邱颖萍,陈志强..磁共振弥散张量成像技术在新生儿脑白质发育中的研究[J].磁共振成像,2015,(4):253-257,5.基金项目
银川市科技攻关资助项目(编号W2011019)；宁夏医科大学重点项目(编号XM2014) （编号W2011019）
