磁共振成像Issue(4)：289-293,5.DOI:10.3969/j.issn.1674-8034.2015.04.009
直肠癌DCE-MRI参数与病理特征的相关性研究
The correlation between DCE-MRI parameters and pathological characteristics in rectal cancer
摘要
Abstract
Abrtract Objective:To evaluate the relationship between the the characteristics of dynamic contrast-enhanced MRI ( DCE-MRI) parameters and the degree of pathologic differentiation as well as Dukes staging in rectal cancer. Materials and Methods:A retrospective investigation of DCE-MRI image of fifty six patients with rectal cancer conifrmed by surgical pathology was made, the time intensity curve (TIC) was rendered, the Ktrans, Ve, Kep parameters graphs were constructed, the characteristics of the TIC, Ktrans, Ve, Kep values as well as the correlation between the degree of tumor differentiation and Dukes stage were analyzed. Results:The TIC of rectal cancer and normal rectal wall around the tumor were divided into three types, in which 8 cases belonged to the type two, 48 cases belonged to the type three. The normal rectal wall around the tumor 41 cases belonged to the type one, 15 cases belonged to the type two. The Ktrans value increase with the worsening of the degree of differentiation and the increase of Dukes staging (P<0.01).There was no statistically signiifcant difference of Ve and Kep values. Conclusions: DCE-MRI can reflect the haemodynamics of internal tumors, TIC and Ktrans value have certain correlation with the degree of pathologic differentiation and Dukes staging. TIC and Ktrans may be used to evaluate the malignancy degree of rectal cancer.关键词
直肠癌/磁共振成像/动态增强/时间-信号强度曲线/容量转移常数Key words
Rectal cancer/Magnetic resonance imaging/Dynamic contrast-enhanced/Time-intensity curve/Volume transfer constant分类
医药卫生引用本文复制引用
谢宗源,徐香玖,黄刚,周星,马小梅,王治民,铁萍,张庆..直肠癌DCE-MRI参数与病理特征的相关性研究[J].磁共振成像,2015,(4):289-293,5.基金项目
甘肃省卫生行业科研计划基金项目(编号GSWST2013-01) （编号GSWST2013-01）
