磁共振成像Issue(4):294-298,5.DOI:10.3969/j.issn.1674-8034.2015.04.010
基于前列腺影像报告和数据系统评估T2WI联合分段读出弥散加权成像诊断早期前列腺癌的价值
Evaluation of T2WI and readout-segmented echo-planar imaging in diagnosing early prostate cancers:a study based on PI-RADS system
摘要
Abstract
Objectives:To compare the clinical utility of readout-segmented echo-planar imaging (RS-EPI) with single-shot echo-planar imaging (SS-EPI) in diagnosing early prostatic cancers. Materials and Methods: Twenty surgically-proved early prostate cancer patients were collected in this retrospective study. T2WI, RS-EPI and SS-EPI were evaluated by two blinded radiologists. By using 6 sub-region classiifcation method the possibility of the presence of cancer at each sub-region was scored according to the PI-RADS system. The receiver operating characteristic (ROC) curve was used to analyze the diagnostic efifcacy of the following 6 protocols: T2WI alone (protocol 1), SS-EPI alone (protocol 2), RS-EPI (protocol 3), a combination of T2WI and SS-EPI (protocol 4) and a combination of T2WI and RS-EPI (protocol 5). Results:The area under the ROC curve (Az) of protocol 1 to protocol 5 for region-based analysis were 0.789, 0.790, 0.874, 0.838, 0.881, respectively. ROC analysis revealed signiifcant differences between protocol 1 and 3, 4, 5, and between protocol 2 and 3, 4, and between protocol 4 and 5 (P<0.05). While the difference between protocol 1 and 2, between 3 and 4, 5 has no statistical significance (P>0.05). Conclusions:The combination of T2WI and DWI can improve the diagnosis ability of early prostate cancers. Combination of T2WI and RS-EPI is a more effective approach than combination of T2WI and SS-EPI for the detection of early prostate cancers.关键词
前列腺肿瘤/磁共振成像/磁共振扩散加权成像Key words
Prostatic neoplasms/Magnetic resonance imaging/Diffusion weighted imaging分类
医药卫生引用本文复制引用
闵祥德,王良,冯朝燕,李亮,蔡杰,邓明,李拔森,可赞,冯定义..基于前列腺影像报告和数据系统评估T2WI联合分段读出弥散加权成像诊断早期前列腺癌的价值[J].磁共振成像,2015,(4):294-298,5.基金项目
国家自然科学基金项目(编号81171307) (编号81171307)