磁共振成像Issue(6)：426-429,4.DOI:10.3969/j.issn.1674-8034.2015.06.006
MRI增强扫描在鼻咽癌放疗近期疗效评估中的应用价值
Value of using contrast-enhanced magnetic resonance imaging for the evaluation of the short-term effects of radiotherapy for nasopharyngeal cancer
摘要
Abstract
Objective:To investigate the value of using contrast-enhanced magnetic resonance imaging (MRI) for efifcient evaluation before and after radical radiotherapy for nasopharyngeal cancer, and to assess whether the use of visual partitioning analysis for tracking and observing nasopharyngeal cancer staging is sensitive to radiotherapy. Materials and Methods:In total, 50 patients who were preliminarily diagnosed with nasopharyngeal cancer through pathological examinations were retrospectively analyzed, including 9 cases with stage T2, 29 cases with T3, and 12 cases with T4. All cases underwent short-term radiotherapy; T1 weighted imaging, T2 weighted imaging, and contrast-enhanced MRI were performed before and after radiotherapy. visual partitioning analysis was used to comparatively measure the variation in morphology and range of foci, as well as the involvement of surrounding tissues. All the above mentioned data were statistically analyzed using independent samplet-tests. Results:Compared to the conditions before radiotherapy, the tumor foci of 9 cases with parapharyngeal space and/or oropharynx involvement, 29 cases with skull base and/or medial pterygoid involvement, and 7 cases with cranial nerve and/or cavernous sinus and/or paranasal sinus and/or lateral pterygoid involvement showed signiifcant shrinkage or reduction in the size of their cervical lymph nodes, along with non-apparent enhancement or no trend in enhancement (P<0.05). However, among 5 T4 cases, the tumor size non-signiifcantly changed in 4 cases and increased in 1 case (P<0.05); moreover, the intensities of the standardized enhancement of foci did not signiifcantly change.Conclusion:The changes in nasopharyngeal cancer before and after radiotherapy can be sensitively determined through contrast-enhanced MRI,which may thus have good clinical applicability in the effective evaluation of nasopharyngeal cancer. Moreover, the efifcacy of radiotherapy fornasopharyngeal cancer may be associated with the pathological staging.关键词
磁共振成像/鼻咽肿瘤/放射治疗Key words
Magnetic resonance imaging/Nasopharyngeal neoplasms/Radiotherapy分类
医药卫生引用本文复制引用
秦方辉,汪洋,孙宗琼,江泓,丁勇俊,蔡炜,岳建国,玄英花,延根..MRI增强扫描在鼻咽癌放疗近期疗效评估中的应用价值[J].磁共振成像,2015,(6):426-429,4.基金项目
教育部留学回国人员科研启动基金(编号2012-1707) （编号2012-1707）
