重庆医学Issue(11)：1308-1311,1314,5.DOI:10.3969/j.issn.1671-8348.2014.11.010
温湿交换器对机械通气患者气道湿化效果的Meta分析
Meta analysis on effect of heat moisture exchangers on airway humidification in mechanically ventilated patients
摘要
Abstract
Objective To assess the effectiveness and safety of heat moisture exchangers (HMEs) on the artificial airway humid-ification in the mechanically ventilated patients .Methods The related literature in the Cochrane Library ,PubMed ,Embase ,CNKI , VIP ,WanFang database and CBM from the establishment to March 2012 were retrieved ,then included the randomized controlled trial(RCT) and quasi-RCT on the effect of HMEs for the artificial airway humidification in the mechanically ventilated patients were performed the meta analysis by using RevMan 5 .1 .2 software .Results 19 RCT were included(involving 2 960 patients) , which were the random parallel controlled trials .The meta analysis results showed that HMEs could not reduce the incidence rate of ventilator-associated pneumonia(VAP)(RR=0 .78 ,95% CI 0 .61-1 .01 ,P=0 .06) ,also could not decrease the hospitalization mor-tality(RR=0 .94 ,95% CI 0 .83-1 .08 ,P=0 .40) ,the length of ICU stay(MD= -0 .32 ,95% CI -3 .13 -2 .50 ,P=0 .82) and the occurrence rate of catheter occlusion (RR=0 .65 ,95% CI 0 .22 -1 .93 ,P= 0 .44) ,the differences between the two groups had no statistical significance .But 5 RCT reported that using HMEs could reduce the patient′s costs .Conclusion HMEs can not reduce the incidence rate of VAP ,mortality ,length of ICU stay ,occurrence rate of airway occlusion ,but can cut down the patient′s cost . Due to the risk of bias existing in all included RCT and the low quality of the obtained evidences ,more strictly designed and imple-mented RCTs are needed to further verify thse evidences .关键词
温湿交换器/通气机,机械/气道湿化/肺炎,呼吸机相关性/Meta分析Key words
heat moisture exchanger/ventilators ,mechanical/airway humidification/pneumonia ,ventilator-associated/Meta-analysis引用本文复制引用
胡汝均,江智霞,郑喜兰,周静,楼婷,李玉..温湿交换器对机械通气患者气道湿化效果的Meta分析[J].重庆医学,2014,(11):1308-1311,1314,5.基金项目
遵义医学院校级重点学科（临床护理学）经费资助。 （）
