重庆医学Issue(12)：1442-1444,3.DOI:10.3969/j.issn.1671-8348.2014.12.012
小量脑出血患者早期康复治疗的临床研究
Clinical study of early rehabilitation treatment in patients with small cerebral hemorrhage
摘要
Abstract
Objective To investigate the effect of early rehabilitation treatment in the patients with small cerebral hemorrhage and its possible mechanisms .Methods 133 patients with cerebral hemorrhage were randomly divided into the routine treatment , non-early rehabilitation and early rehabilitation groups and given the routine drug treatment .The early rehabilitation group and the non-early rehabilitation group were additionally given the rehabilitative training after 2 d and 14 d respectively .The scores of Fugl-Meyer reassessment and the Barthel index were assessed before training and after 4-week training ,and the serum levels of circulat-ing endotheial progenitor cells(EPCs) and vascular endotheial cell growth factors(VEGF) were detected .Results Compared with the routine treatment group and the non-early rehabilitation group ,the scores of Fugl-Meyer reassessment and the Barthel index af-ter treatment in the early rehabilitation group were significantly increased (P< 0 .01) .The serum levels of circulating EPCs and VEGF in the early rehabilitation group were also significantly increased compared with the routine treatment group control (P<0 .01) .Conclusion Early rehabilitation treatment can obviously improve the limb movement function and the daily living ability in the patients with small cerebral hemorrhage ,its mechanisms may be involved with the increase of circulating EPCs and VEGF .关键词
脑出血/早期康复/Fugl-Meyer评分/Barthel指数/内皮/干细胞/血管内皮生长因子Key words
cerebral hemorrhage/early rehabilitation/Fugl-Meyer reassessment/Barthel index/endothelium/stem cells/vascular endothelial growth factor引用本文复制引用
林敏,邹少娜..小量脑出血患者早期康复治疗的临床研究[J].重庆医学,2014,(12):1442-1444,3.基金项目
2012年湖南省教育厅课题资助项目（12C0218）。 （）
