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3种2型糖尿病治疗方案的成本-效果分析

刘全义 彭斌 李启富 李蓉 龚莉琳 秧茂盛

重庆医学Issue(19):2470-2473,4.
重庆医学Issue(19):2470-2473,4.DOI:10.3969/j.issn.1671-8348.2014.19.025

3种2型糖尿病治疗方案的成本-效果分析

Cost-effectiveness analysis of three therapeutic schemes for type 2 diabetes mellitus

刘全义 1彭斌 2李启富 3李蓉 3龚莉琳 3秧茂盛4

作者信息

  • 1. 重庆医科大学药学院药理教研室 400016
  • 2. 重庆医科大学公共卫生与管理学院统计学教研室 400016
  • 3. 重庆医科大学第一附属医院内分泌科 400016
  • 4. 吉首大学医学院药理教研室与疾病基因研究室,湖南吉首416000
  • 折叠

摘要

Abstract

Objective To compare and analyze of three therapeutic schemes for type 2 diabetes mellitus(T2DM ) using the cost-effectiveness .Methods Using the basic idea of pharmacoeconomics evaluate cost-effect analysis method for three therapeutic schemes(oral glucose-lowering drugs ,oral glucose-lowering drugs + insulin injection one time ,oral glucose-lowering drugs + insu-lin injection twice) .Results The three therapeutic schemes average cost of arrived to 827 .30 yuan/3 months ,1 714 .50 yuan/3 months and 1 087 .50 yuan/3 months ,respectively(P=0 .00);the efficiency of control fasting blood glucose were 56 .51% ,51 .69%and 57 .04% ,respectively (P=0 .754);the efficiency of control 2 h postprandial blood glucose were 50 .56% ,40 .68% and 55 .63% , respectively (P=0 .097);the cost-effectiveness ratio of fasting blood glucose were 14 .64 ,33 .17 and 19 .06 ,respectively ;the cost-ef-fectiveness ratio of 2 h postprandial blood sugar were 16 .36 ,42 .15 and 19 .55 ,respectively .For the oral glucose-lowering drugs group as reference ,the cost-effective ratioscost of control fasting blood glucose and control 2 h postprandial blood glucose were -184 .4 and -89 .8 for oral glucose-lowering drugs + insulin injection one time ,respectively ;the cost-effective ratioscost of control fasting blood glucose and control 2 h postprandial blood glucose were 484 .8 and 51 .26 for oral glucose-lowering drugs + insulin in-jection twice ,respectively .Conclusion According to the principles of economics ,oral medication has the highest cost-effectiveness ratio in the treatment for T 2DM ,and oral medication + insulin injection twice has better therapeutic efficacy .

关键词

经济学 ,药学/糖尿病 ,2型/成本-效果分析

Key words

economics ,pharmaceutical/diabetes mellitus ,type 2/cost-effectiveness analysis

分类

医药卫生

引用本文复制引用

刘全义,彭斌,李启富,李蓉,龚莉琳,秧茂盛..3种2型糖尿病治疗方案的成本-效果分析[J].重庆医学,2014,(19):2470-2473,4.

重庆医学

OA北大核心CSTPCD

1671-8348

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