重庆医学Issue(20)：2617-2619,3.DOI:10.3969/j.issn.1671-8348.2014.20.026
F as-670基因多态性与青海地区乳腺癌临床病理指标间的关系
The association between Fas-670 gene polymorphisms and clinic pathologic index of breast cancer in Qinghai district
摘要
Abstract
Objective To investigate the correlation between Fas-670 gene polymorphisms and the clinic pathologic index of breast cancer in Qinghai district .Methods The polymorphisms of Fas-670 gene were detected by polymerase chain reaction-restric-tion fragment length polymorphisms assay (PCR-RFLP) in 232 female breast cancer patients ,χ2 test was applied to assess the asso-ciation between the polymorphisms of Fas-670 gene and breast cancer clinic pathologic index .Results In 232 breast cancer pa-tients ,the frequency of Fas-670 homozygous wild type(AA) ,heterozygous type(AG) ,homozygous mutant type(GG) were 39 .7%(92/232) ,48 .7% (113/232) ,11 .6% (27/232) respectively .It was no statistical significance between Fas-670 gene polymorphisms and the clinic pathologic index of breast cancer in Qinghai district(P>0 .05) .Conclusion The polymorphisms of Fas-670 gene is not associated with clinic pathologic index of breast cancer in Qinghai district .关键词
乳腺肿瘤/Fas-670/基因多态性/临床病理指标Key words
breast neoplasms/Fas-670/gene polymorphisms/clinic pathologic index分类
医药卫生引用本文复制引用
黄欣,胡英,王秀娟,金丽艳,张双元..F as-670基因多态性与青海地区乳腺癌临床病理指标间的关系[J].重庆医学,2014,(20):2617-2619,3.基金项目
国家自然科学基金资助项目（30960359）。 （）
