重庆医学Issue(21)：2730-2733,4.DOI:10.3969/j.issn.1671-8348.2014.21.015
吸入性糖皮质激素与孟鲁司特治疗儿童哮喘疗效的M eta分析
Meta-analysis of studies on inhaled corticosteroids and montelukast in children with asthma
郭梅 1符州2
作者信息
- 1. 重庆医科大学附属儿童医院呼吸科 400014
- 2. 重庆市合川区人民医院儿科 401520
- 折叠
摘要
Abstract
Objective To compare the effect of inhaled corticosteroids and montelukast in children with asthma .Methods Data were obtained from Pubmed ,Embase and Central databases ,CNKI and VIP .Only randomized controlled trials (RCT ) that evalua-ting inhaled corticosteroids and montelukast for children were included .The Cochrane collaboration risk bias tools was used to eval-uated the quality of literature .Results The patients with inhaled corticosteroids had a better effect in FEV 1% and PEF than pa-tients with montelukast ,the incidences of adverse drug reactions had no statistically significant difference .The patients with inhaled corticosteroids combined with montelukast had a better effect in FEV 1% or PEF than patients with inhaled corticosteroids only . Conclusion The effect of inhaled corticosteroids is better than montelukast ,the effect of inhaled corticosteroids combined with montelukast is better than inhaled corticosteroids only ,and has drug safety .关键词
儿童急性哮喘/吸入性糖皮质激素/孟鲁司特Key words
children with acute asthma/inhaled corticosteroids/montelukast分类
医药卫生引用本文复制引用
郭梅,符州..吸入性糖皮质激素与孟鲁司特治疗儿童哮喘疗效的M eta分析[J].重庆医学,2014,(21):2730-2733,4.
