重庆医学Issue(21)：2736-2738,3.DOI:10.3969/j.issn.1671-8348.2014.21.017
茶多酚对酒精性肝损伤过氧化的影响
Effect of tea polyphenols intake on ethanol-induced liver injury
唐袁婷 1管小琴 2江咏梅 1岳新爱 1陈平 1彭英 1玉洁1
作者信息
- 1. 四川大学华西第二医院检验科，成都610041
- 2. 重庆医科大学附属第一医院病理科 400016
- 折叠
摘要
Abstract
Objective To establish the cell model of ethanol-induced liver injury and explore the protective effects of tea poly-phenols (TP)on ethanol-induced liver injury .Methods Cell morphology were observed by microscope ,and then alanine aminotrans-ferase (ALT) ,nmda transaminase (AST) ,gamma GGTP ,GGT and ROS changes were detected .Results Alcohol maked L02 hepa-tocyte fatty degeneration .Compared with ethanol group ,steatosis in TP + ethanol group was lighter ,its ALT ,AST ,GGT content and intracellular ROS reduced .Conclusion TP can decrease cell fatty change degree in vitro experiments ,improue the enzymology indexes ,reduce the generation of reactive oxygen species to avoid liver damage .关键词
茶多酚/酒精性肝损伤/过氧化Key words
tea polyphenols/ethanol-induced liver injury/ROS分类
医药卫生引用本文复制引用
唐袁婷,管小琴,江咏梅,岳新爱,陈平,彭英,玉洁..茶多酚对酒精性肝损伤过氧化的影响[J].重庆医学,2014,(21):2736-2738,3.
