重庆医学Issue(22):2853-2854,2858,3.DOI:10.3969/j.issn.1671-8348.2014.22.008
益艾康胶囊对无症状期HIV感染者T淋巴细胞亚群的影响
The effect of Yiaikang capsules on T lymphocyte subsets of asymptomatic HIV infected patients
摘要
Abstract
Objective To explore the effect of Yiaikang capsule on T lymphocyte subsets of asymptomatic HIV infected pa-tients ,and look for sensitive indicator which can reflect the therapeutic effect of HIV drug .Methods Peripheral venous blood sam-ples were collected from Yiaikang capsule treated and untreated asymptomatic HIV infected patients .Flow cytometry was used to detect T lymphocyte count and the T lymphocyte subsets percentage in the venous blood .Results The percentages of CD4+ ,CD4+CD45RA+ ,CD4+CD45RO+ ,CD4+ CD28+ ,and CD4+ CD95+ T cells in Yiaikang treatment group were significantly higher than that of control group(P<0 .05) ,while the percentages of CD8+ ,CD8+CD38+ T cells were significantly lower than that of control group(P<0 .05) .Conclusion Yiaikang capsule can effectively slow the decrease of CD4+ T lymphocyte subgroup in asymptomatic HIV infected patients and promote the activation of CD 4+ T lymphocytes .关键词
HIV/益艾康胶囊/T淋巴细胞亚群Key words
HIV/Yiaikang capsule/T lymphocyte subsets分类
医药卫生引用本文复制引用
刘萍萍,李倩如,轩小燕,董子明,王哲,杜英..益艾康胶囊对无症状期HIV感染者T淋巴细胞亚群的影响[J].重庆医学,2014,(22):2853-2854,2858,3.基金项目
河南省医学科技攻关项目(2011010016);河南省医学科技攻关项目(2011020079)。 ()