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益艾康胶囊对无症状期HIV感染者T淋巴细胞亚群的影响

刘萍萍 李倩如 轩小燕 董子明 王哲 杜英

重庆医学Issue(22):2853-2854,2858,3.
重庆医学Issue(22):2853-2854,2858,3.DOI:10.3969/j.issn.1671-8348.2014.22.008

益艾康胶囊对无症状期HIV感染者T淋巴细胞亚群的影响

The effect of Yiaikang capsules on T lymphocyte subsets of asymptomatic HIV infected patients

刘萍萍 1李倩如 1轩小燕 1董子明 2王哲 3杜英1

作者信息

  • 1. 郑州大学基础医学院 微生物学与免疫学教研室,郑州450001
  • 2. 郑州大学基础医学院 病理生理学教研室,郑州450001
  • 3. 河南省疾病控制中心性病艾滋病研究所,郑州450016
  • 折叠

摘要

Abstract

Objective To explore the effect of Yiaikang capsule on T lymphocyte subsets of asymptomatic HIV infected pa-tients ,and look for sensitive indicator which can reflect the therapeutic effect of HIV drug .Methods Peripheral venous blood sam-ples were collected from Yiaikang capsule treated and untreated asymptomatic HIV infected patients .Flow cytometry was used to detect T lymphocyte count and the T lymphocyte subsets percentage in the venous blood .Results The percentages of CD4+ ,CD4+CD45RA+ ,CD4+CD45RO+ ,CD4+ CD28+ ,and CD4+ CD95+ T cells in Yiaikang treatment group were significantly higher than that of control group(P<0 .05) ,while the percentages of CD8+ ,CD8+CD38+ T cells were significantly lower than that of control group(P<0 .05) .Conclusion Yiaikang capsule can effectively slow the decrease of CD4+ T lymphocyte subgroup in asymptomatic HIV infected patients and promote the activation of CD 4+ T lymphocytes .

关键词

HIV/益艾康胶囊/T淋巴细胞亚群

Key words

HIV/Yiaikang capsule/T lymphocyte subsets

分类

医药卫生

引用本文复制引用

刘萍萍,李倩如,轩小燕,董子明,王哲,杜英..益艾康胶囊对无症状期HIV感染者T淋巴细胞亚群的影响[J].重庆医学,2014,(22):2853-2854,2858,3.

基金项目

河南省医学科技攻关项目(2011010016);河南省医学科技攻关项目(2011020079)。 ()

重庆医学

OA北大核心CSTPCD

1671-8348

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