摘要
Abstract
Objective To investigate the relationship between subclinical hypothyroidism and ambulatory blood pressure in the patients with menopause hypertension .Methods 45 menopause hypertensive patients complicated with subclinical hypothyroidism (group A)and 58 menopause hypertensive patients(group B)were studied .Systolic blood pressure ,diastolic blood pressure ,height , body mass ,urea nitrogen ,serum creatinine ,uric acid ,fasting plasma glucose ,blood lipid level ,thyroid function and 24 hours ambula-tory blood pressure were measured .Results The levels of diastolic blood pressure ,24 hours diastolic blood pressure were higher in group A than those in group B[(89 .76 ± 11 .54)mm Hg vs .(80 .18 ± 10 .37)mm Hg ,(81 .05 ± 10 .45)mm Hg vs .(75 .46 ± 8 .73) mm Hg ,P<0 .01] .SBP and DBP nocturnal dipping were lower in group A than those in group B [(6 .43 ± 3 .56)% vs .(10 .35 ± 7 .63)% ,(8 .49 ± 6 .35)% vs .(13 .02 ± 8 .92)% ,P<0 .01] .The proportion of non-dipper patients was higher in group A than that in group B(62 .22% vs .39 .66% ,P<0 .05) .Multiple linear regression analysis showed that diastolic blood pressure decreased with the increasing of age ,and increased with the increasing of serum thyrotropin level .Nocturnal dipping decreased with the increasing of BMI and serum thyrotropin level .Conclusion Thyroid function tests should be performed in menopause hypertensive patients with poorly controlled diastolic blood pressure and non-dipping ,which contributes to the diagnosis of hypertension etiology .关键词
高血压/亚临床甲状腺功能减退/24 h动态血压/血清促甲状腺激素/更年期Key words
hypertension/subclinical hypothyroidism/24 hours ambulatory blood pressure/serum thyrotropin/menopause分类
医药卫生
