重庆医学Issue(24)：3121-3123,3126,4.DOI:10.3969/j.issn.1671-8348.2014.24.001
甲磺酸双氢麦角毒碱治疗缺血性卒中所致头痛的疗效观察
The therapeutic efficacy of dihydroergotoxine for headache attributed to ischemic stroke
摘要
Abstract
Objective This clinical study was designed to explore the therapeutic efficacy of dihydroergotoxine for headache at-tributed to ischemic stroke .Methods Seventy eight patients fulfilling the diagnostic criteria of headache attributed to ischemic stroke were enrolled and randomly divided into two treatment group(n=42) and control group(n=36) who took dihydroergotoxine (2 mg twice daily) and placebo respectively .One week for a course of treatment ,had many courses of treatment .Efficacy was as-sessed using the patient′s diary .Results The gender ,age ,stroke aetiology ,admission NIHSS score ,quality and location of headache didn′t differ significantly between the two groups .Compared with the control group ,the duration of headache were shorter in treat-ment group(3 .78 ± 1 .44 vs .4 .88 ± 1 .45 ,P=0 .002) .The severity of headache were lower in treatment group since the third day post ischemic stroke(P<0 .05) .There were no significant side effects during treatment .Conclusion Dihydroergotoxine in treat-ment of headache attributed to ischemic stroke is beneficial to shorten the duration of headache as well as decrease the severity of headache ,and thereby improve the quality of life .关键词
甲磺酸双氢麦角毒碱/缺血性卒中/头痛/疗效Key words
dihydroergotoxine/ischemic stroke/headache/therapeutic efficacy分类
医药卫生引用本文复制引用
吕玉花,谭戈..甲磺酸双氢麦角毒碱治疗缺血性卒中所致头痛的疗效观察[J].重庆医学,2014,(24):3121-3123,3126,4.基金项目
教育部高等学校博士学科点专项科研基金联合资助课题（20115503120008）；国家自然科学基金资助项目（30970988）。 （）
