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光动力疗法联合 Lucentis 玻璃体腔注射治疗 CNV 的疗效观察

罗文彬 游志鹏

重庆医学Issue(31):4213-4215,3.
重庆医学Issue(31):4213-4215,3.DOI:10.3969/j.issn.1671-8348.2014.31.031

光动力疗法联合 Lucentis 玻璃体腔注射治疗 CNV 的疗效观察

Clinical observation of photodynamic therapy combined with vitreous cavity injection of Lucentis treatment for choroidal neovascularization diseases

罗文彬 1游志鹏1

作者信息

  • 1. 南昌大学第二附属医院眼科,南昌 330006
  • 折叠

摘要

Abstract

Objective To investigate the efficacy and safety of photodynamic therapy(PDT) combined with vitreous cavity injec‐tion of Lucentis treatment for choroidal neovascularization(CNV) diseases .Methods we retrospectively analyzed data of 30 cases (30 eyes) of CNV ,who was diagnosed by examination of visual acuity ,intmocular pressure ,ocular fundus ,fundus fluorescein angi‐ography (FFA) ,and optic coherence tomography(OCT) ,and who underwent PDT combined with intravitreal injection of Lucentis . Results At the 4 ~ 6 months follow‐up ,the best corrected visual acuity(BCVA) improved in 22 eyes(73 .3% ) ,stabilized in 8 eyes (26 .7% ) and none decreased .Among the AMD ,14 cases(70 .0% ) required only a single combined treatment for CNV resolution ;3 cases of AMD needed retreatment 3 months later .In CNV group ,all of the cases required only a single combined treatment for CNV resolution .At the therapy and follow‐up period ,no ocular or systemic adverse reactions were noted .Conclusion The treatment of PDT combine intravitreal injection of Lucentis is safe and effective for CNV ,which could improve visual acuity and reduce retreat‐ment rates .

关键词

光化学疗法/Lucentis/玻璃体腔注射/联合治疗/脉络膜新生血管

Key words

photochemotherapy/Lucentis/intravitreal/combined treatment/choroidal neovascularization

分类

医药卫生

引用本文复制引用

罗文彬,游志鹏..光动力疗法联合 Lucentis 玻璃体腔注射治疗 CNV 的疗效观察[J].重庆医学,2014,(31):4213-4215,3.

重庆医学

OA北大核心CSTPCD

1671-8348

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