重庆医学Issue(33)：4460-4461,2.DOI:10.3969/j.issn.1671-8348.2014.33.014
慢性肾脏疾病患者血清半乳糖凝集素-3检测的临床意义
Serum level of galectin 3 and its clinical significance in patients with chronic kidney disease
摘要
Abstract
Objective To detect serum galectin 3 levels in patients with chronic kidney disease (CKD) and explore its clinical significance .Methods The galectin 3 levels the serum of in 38 CKD patients and 34 healthy controls were determined by ELISA . All kidney function was measured by automatic biochemical analyzer .The relation between serum galectin 3 levels and the level of kidney function was analyzed by use of t test .Results The serum galectin 3 levels in CKD and healthy controls groups were (1 .22 ± 1 .01)ng/mL and (3 .03 ± 2 .06)ng/mL ,P<0 .05 .There was close negative correlation between serum levels of galectin 3 and Cr ,CysC(P<0 .05) .Conclusion Serum galectin 3 of CKD patients reduces significantly and correlates with kidney function . Detecting on s galectin 3 is helpful for chronic kidney disease diagnosis and therapeutic effect evaluation .关键词
半乳糖凝集素3/慢性肾脏疾病/肾功能Key words
galectin 3/chronic kidney disease/renal function分类
医药卫生引用本文复制引用
赖冬,熊咏梅,龙敏,张以勤..慢性肾脏疾病患者血清半乳糖凝集素-3检测的临床意义[J].重庆医学,2014,(33):4460-4461,2.基金项目
厦门市科技局科技计划项目（3502z20134030）。 （）
