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口服普萘洛尔治疗婴幼儿血管瘤的临床研究

郭军 王宇 张毅 余静 刘亚琼 谢坚

重庆医学Issue(33):4464-4466,3.
重庆医学Issue(33):4464-4466,3.DOI:10.3969/j.issn.1671-8348.2014.33.016

口服普萘洛尔治疗婴幼儿血管瘤的临床研究

Clinical research on the effects of propranolol on infantile hemangiomas

郭军 1王宇 2张毅 1余静 1刘亚琼 1谢坚1

作者信息

  • 1. 四川省绵阳市中心医院 儿科 621000
  • 2. 四川省绵阳市中心医院 药剂科 621000
  • 折叠

摘要

Abstract

Objective To study the efficacy and adverse reactions of the treatment on different types of infantile hemangiomas (IH) with different doses of propranolol .Methods One hundred and fifty cases of IH without contraindications were randomly treated with different doses of propranolol (low dose group:1 mg・kg -1 ・d-1 ;high dose group:2 mg・kg -1 ・d-1 ) under ECG monitoring inferior half an hour to breastfeeding taking ,and stay in hospital for observation for 6 to 24 hours after the treatment . The patients returned to the hospital for review every month(ECG and blood RT ;lung function in necessary) .Results The curative effect is better on strawberry IH than that on flat IH ,also better on deeply IH than that on superficial IH .The adverse reactions oc‐curred relatively slight in the low dose group and there was no significantly statistical differences on the treatment effects between the both groups(P>0 .05) .Conclusion It is safe and effective to treat IH with propranolol .

关键词

普萘洛尔/婴幼儿血管瘤/疗效

Key words

propranolol/infantile hemangiomas/curative effect

分类

医药卫生

引用本文复制引用

郭军,王宇,张毅,余静,刘亚琼,谢坚..口服普萘洛尔治疗婴幼儿血管瘤的临床研究[J].重庆医学,2014,(33):4464-4466,3.

基金项目

四川省卫生厅科研课题(100320);绵阳市中心医院课题(2014YJ22)。 ()

重庆医学

OA北大核心CSTPCD

1671-8348

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