重庆医学Issue(33):4464-4466,3.DOI:10.3969/j.issn.1671-8348.2014.33.016
口服普萘洛尔治疗婴幼儿血管瘤的临床研究
Clinical research on the effects of propranolol on infantile hemangiomas
摘要
Abstract
Objective To study the efficacy and adverse reactions of the treatment on different types of infantile hemangiomas (IH) with different doses of propranolol .Methods One hundred and fifty cases of IH without contraindications were randomly treated with different doses of propranolol (low dose group:1 mg・kg -1 ・d-1 ;high dose group:2 mg・kg -1 ・d-1 ) under ECG monitoring inferior half an hour to breastfeeding taking ,and stay in hospital for observation for 6 to 24 hours after the treatment . The patients returned to the hospital for review every month(ECG and blood RT ;lung function in necessary) .Results The curative effect is better on strawberry IH than that on flat IH ,also better on deeply IH than that on superficial IH .The adverse reactions oc‐curred relatively slight in the low dose group and there was no significantly statistical differences on the treatment effects between the both groups(P>0 .05) .Conclusion It is safe and effective to treat IH with propranolol .关键词
普萘洛尔/婴幼儿血管瘤/疗效Key words
propranolol/infantile hemangiomas/curative effect分类
医药卫生引用本文复制引用
郭军,王宇,张毅,余静,刘亚琼,谢坚..口服普萘洛尔治疗婴幼儿血管瘤的临床研究[J].重庆医学,2014,(33):4464-4466,3.基金项目
四川省卫生厅科研课题(100320);绵阳市中心医院课题(2014YJ22)。 ()