重庆医学Issue(1)：21-23,3.DOI:10.3969/j.issn.1671-8348.2015.01.007
青蒿素对肝癌细胞株HepG2细胞增殖的影响
The effect of artemisinin on the proliferation of human hepatoma cell line HepG-2
摘要
Abstract
Objective To investigate the effect of artemisinin on the proliferation of human hepatoma cell line HepG‐2 .Methods The inhibition effect of cell proliferation in human hepatocelluar carcinoma cell line HepG2 of artemisinin was detected by MTT test ,and the cell cycle and apoptosis were detected by Flow cytometry .Results Artemisinin at 80 umol/L could effectively inhibi‐ted the proliferation of HepG‐2 cell in a dose‐and time‐dependent manner;the drugs could block cells at G0/S phase ,and induct the HepG‐2 cell apoptosis .Conclusion Artemisinin could effectively inhibit the proliferation of HepG‐2 cell .关键词
青蒿素/肝肿瘤/流式细胞术/细胞周期/细胞凋亡Key words
artemisinin/liver neoplasms/flow cytometry/cell cycle/apoptosis分类
医药卫生引用本文复制引用
黄俊玲,李广志,黄赞松,尹毅霞,周喜汉,覃月秋..青蒿素对肝癌细胞株HepG2细胞增殖的影响[J].重庆医学,2015,(1):21-23,3.基金项目
广西自然科学基金课题（桂科自0542119）；广西医疗卫生重点科研课题（桂卫重200887）；广西中医药管理局课题（桂卫中gzzc0955）。 （）
